Results 31 to 40 of about 1,331,499 (342)

Simulating Cortical Feedback Modulation as Changes in Excitation and Inhibition in a Cortical Circuit Model. [PDF]

, 2016
Cortical feedback pathways are hypothesized to distribute context-dependent signals during flexible behavior. Recent experimental work has attempted to understand the mechanisms by which cortical feedback inputs modulate their target regions.
McCormick, David A, Murray, John D, Zagha, Edward   +2 more
core   +2 more sources

Cellular imaging of visual cortex reveals the spatial and functional organization of spontaneous activity

Frontiers in Integrative Neuroscience, 2010
The cerebral cortex is never silent; even in primary sensory areas there is ongoing neural activity in the absence of sensory input. Correlations in spontaneous activity can provide clues about network structure, but it has been difficult to record from ...
Yeang H Ch'Ng, Clay Reid
doaj   +1 more source

cAMP-Dependent Co-stabilization of Axonal Arbors from Adjacent Developing Neurons

Cell Reports, 2020
Summary: Axonal arbors in many neuronal networks are exuberant early during development and become refined by activity-dependent competitive mechanisms. Theoretical work proposed non-competitive interactions between co-active axons to co-stabilize their ...
Alice Louail, Martijn C. Sierksma, Antoine Chaffiol, Sarah Baudet, Ahlem Assali, Sandrine Couvet, Melissa Nedjam, Fiona Roche, Yvrick Zagar, Jens Duebel, Xavier Nicol   +10 more
doaj   +1 more source

Multiple independent oscillatory networks in the degenerating retina

Frontiers in Cellular Neuroscience, 2015
During neuronal degenerative diseases, microcircuits undergo severe structural alterations, leading to remodeling of synaptic connectivity. This can be particularly well observed in the retina, where photoreceptor degeneration triggers rewiring of ...
Thomas eEuler, Timm eSchubert
doaj   +1 more source

Using Light-Sheet Microscopy to Study Spontaneous Activity in the Developing Lateral-Line System

Frontiers in Cell and Developmental Biology, 2022
Hair cells are the sensory receptors in the auditory and vestibular systems of all vertebrates, and in the lateral-line system of aquatic vertebrates.
Qiuxiang Zhang, Katie S. Kindt
doaj   +1 more source

Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy

Frontiers in Neural Circuits, 2013
The optical transparency and the small dimensions of zebrafish at the larval stage make it a vertebrate model of choice for brain-wide in-vivo functional imaging.
Thomas ePanier, Sebastian eRomano, Raphaël eOlive, Thomas ePietri, German eSumbre, Raphaël eCandelier, Georges eDebrégeas   +6 more
doaj   +1 more source

Cellular antiseizure mechanisms of everolimus in pediatric tuberous sclerosis complex, cortical dysplasia, and non-mTOR-mediated etiologies. [PDF]

, 2018
The present study was designed to examine the potential cellular antiseizure mechanisms of everolimus, a mechanistic target of rapamycin (mTOR) pathway blocker, in pediatric epilepsy cases. Cortical tissue samples obtained from pediatric patients (n 
Barry, Joshua, Cepeda, Carlos, Fallah, Aria, Levine, Michael S, Levinson, Simon, Mathern, Gary W, Vinters, Harry V, Wu, Joyce Y, Yazon, Vannah-Wila   +8 more
core   +2 more sources

Alpha2-Containing Glycine Receptors Promote Neonatal Spontaneous Activity of Striatal Medium Spiny Neurons and Support Maturation of Glutamatergic Inputs

Frontiers in Molecular Neuroscience, 2018
Glycine receptors (GlyRs) containing the α2 subunit are highly expressed in the developing brain, where they regulate neuronal migration and maturation, promote spontaneous network activity and subsequent development of synaptic connections. Mutations in
Joris Comhair, Joris Comhair, Jens Devoght, Giovanni Morelli, Robert J. Harvey, Robert J. Harvey, Victor Briz, Victor Briz, Sarah C. Borrie, Sarah C. Borrie, Claudia Bagni, Claudia Bagni, Jean-Michel Rigo, Serge N. Schiffmann, David Gall, Bert Brône, Svetlana M. Molchanova   +16 more
doaj   +1 more source

A functional network of highly pure enteric neurons in a dish

Frontiers in Neuroscience, 2023
The enteric nervous system (ENS) is the intrinsic nervous system that innervates the entire digestive tract and regulates major digestive functions. Recent evidence has shown that functions of the ENS critically rely on enteric neuronal connectivity ...
Martial Caillaud, Morgane E. Le Dréan, Adrien De-Guilhem-de-Lataillade, Catherine Le Berre-Scoul, Jérôme Montnach, Steven Nedellec, Gildas Loussouarn, Vincent Paillé, Michel Neunlist, Hélène Boudin   +9 more
doaj   +1 more source

Neural Avalanches at the Critical Point between Replay and Non-Replay of Spatiotemporal Patterns [PDF]

, 2013
We model spontaneous cortical activity with a network of coupled spiking units, in which multiple spatio-temporal patterns are stored as dynamical attractors.
de Candia, Antonio, Scarpetta, Silvia
core   +3 more sources