Results 51 to 60 of about 1,331,499 (342)
Frontiers in Cellular Neuroscience, 2018 During development, the sensory cells of the cochlea, the inner hair cells (IHCs), fire spontaneous calcium action potentials. This activity at the pre-hearing stage allows the IHCs to autonomously excite the auditory nerve fibers and hence, represents ...
Anne-Gabrielle Harrus +5 more
doaj +1 more source
Brain modularity controls the critical behavior of spontaneous activity
, 2014 The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network.
de Arcangelis, Lucilla +2 more
core +1 more source
Repeating Spatial-Temporal Motifs of CA3 Activity Dependent on Engineered Inputs from Dentate Gyrus Neurons in Live Hippocampal Networks. [PDF]
, 2016 Anatomical and behavioral studies, and in vivo and slice electrophysiology of the hippocampus suggest specific functions of the dentate gyrus (DG) and the CA3 subregions, but the underlying activity dynamics and repeatability of information processing ...
Bhattacharya, Aparajita +4 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Enhanced Retention In The Passive-Avoidance Task By 5-HT1A Receptor Blockade Is Not Associated With Increased Activity Of The Central Nucleus Of The Amygdala [PDF]
, 2003 The effect of blockade of S-HT1A receptors was investigated on (1) retention in a mildly aversive passive-avoidance task, and (2) spontaneous single-unit activity of central nucleus of the amygdala (CeA) neurons, a brain site implicated in modulation of ...
Everbach, E. Carr +5 more
core +1 more source
Complex Spontaneous Flows and Concentration Banding in Active Polar Films [PDF]
, 2008 We study the dynamical properties of active polar liquid crystalline films. Like active nematic films, active polar films undergo a dynamical transitions to spontaneously flowing steady-states.
Giomi, Luca +2 more
core +3 more sources
How not to study spontaneous activity
NeuroImage, 2009 Brains are restless. We have long known of the existence of a great deal of uninterrupted brain activity that maintains the body in a stable state--from an evolutionary standpoint one of the brain's most ancient tasks. But intrinsic, ongoing activity is not limited to subcortical, life-maintaining structures; cortex, too, is remarkably active even in ...
Logothetis, Nikos +6 more
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons [PDF]
, 2014 Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na+ channels in OSNs to assess their role in spontaneous activity.
Dionne, Vincent E. +6 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source