Results 61 to 70 of about 7,170,848 (305)

Monkey in the middle: Why nonhuman primates are needed to bridge the gap in resting-state investigations

open access: yesFrontiers in Neuroanatomy, 2012
Resting-state investigations based on the evaluation of intrinsic low-frequency fluctuations of the BOLD fMRI signal have been extensively utilized to map the structure and dynamics of large-scale functional network organization in humans. In addition to
R. Matthew eHutchison   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

On the Origin of the 1,000 Hz Peak in the Spectrum of the Human Tympanic Electrical Noise

open access: yesFrontiers in Neuroscience, 2017
The spectral analysis of the spontaneous activity recorded with an electrode positioned near the round window of the guinea pig cochlea shows a broad energy peak between 800 and 1,000 Hz. This spontaneous electric activity is called round window noise or
Javiera Pardo-Jadue   +6 more
doaj   +1 more source

Spontaneous activity.

open access: yes, 2013
(A–C) Spontaneous multi-unit activity (MUA) simultaneously recorded in the forepaw cortex (black) and hindpaw cortex (gray) under three different conditions in a representative animal: (A) intact animal under lighter anesthesia, (B) intact animal under ...
Guglielmo Foffani (287632)   +2 more
core   +1 more source

Structural determinants and regulation of spontaneous activity in GABAA receptors [PDF]

open access: yes, 2021
GABA_{A} receptors are vital for controlling neuronal excitability and can display significant levels of constitutive activity that contributes to tonic inhibition. However, the mechanisms underlying spontaneity are poorly understood. Here we demonstrate
Sexton, CA   +4 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Baseline Brain Activity Changes in Patients With Single and Relapsing Optic Neuritis

open access: yesFrontiers in Human Neuroscience, 2018
Purpose: To investigate spontaneous brain activity amplitude alterations in single and relapsing optic neuritis (sON and rON, respectively) and their relationships with clinical variables.Methods: In total, 42 patients with sON, 35 patients with rON and ...
Zhuoqiong Ren   +15 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Bessel Beam Illumination Reduces Random and Systematic Errors in Quantitative Functional Studies Using Light-Sheet Microscopy

open access: yesFrontiers in Cellular Neuroscience, 2018
Light-sheet microscopy (LSM), in combination with intrinsically transparent zebrafish larvae, is a method of choice to observe brain function with high frame rates at cellular resolution.
M. Caroline Müllenbroich   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy