Results 81 to 90 of about 7,170,848 (305)

Disrupted resting-state spontaneous neural activity in stable COPD

, 2019
Huizhen Xin,1,* Haijun Li,1,* Honghui Yu,1 Jingjing Yu,2 Juan Zhang,1 Wenjing Wang,2 Dechang Peng1 1Department of Radiology, The First Affiliated Hospital, Nanchang University, Nanchang, People’s Republic of China; 2Department of Respiratory, The ...
Li H, Peng D, Zhang J, Wang W, Xin H, Yu J, Yu H   +6 more
core  

Adaptation of spontaneous activity in the developing visual cortex

, 2021
Spontaneous activity drives the establishment of appropriate connectivity in different circuits during brain development. In the mouse primary visual cortex, two distinct patterns of spontaneous activity occur before vision onset: local low-synchronicity
Zabouri, N., Lohmann, Christian, Gjorgjieva, Julijana, Chao, L., Wosniack, M., Lohmann, C., Chao, Ling Ya, Wosniack, Marina E., Christian Lohmann, Gjorgjieva, J., Nawal Zabouri, Zabouri, Nawal, Jan H Kirchner, Julijana Gjorgjieva, Kirchner, J., Marina E Wosniack, Kirchner, Jan H., Ling-Ya Chao   +17 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Presbycusis Disrupts Spontaneous Activity Revealed by Resting-State Functional MRI

Frontiers in Behavioral Neuroscience, 2018
Purpose: Presbycusis, age-related hearing loss, is believed to involve neural changes in the central nervous system, which is associated with an increased risk of cognitive impairment.
Yu-Chen Chen, Yu-Chen Chen, Huiyou Chen, Liang Jiang, Fan Bo, Jin-Jing Xu, Cun-Nan Mao, Richard Salvi, Xindao Yin, Guangming Lu, Jian-Ping Gu   +10 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Self-specific stimuli interact differently than non-self-specific stimuli with eyes-open versus eyes-closed spontaneous activity in auditory cortex

Frontiers in Human Neuroscience, 2013
Previous studies suggest that there may be a distinct relationship between spontaneous neural activity and subsequent or concurrent self-specific stimulus-induced activity. This study aims to test the impact of spontaneous activity as recorded in an eyes-
Pengmin eQin, Simone eGrimm, Niall W Duncan, Giles eHolland, Jia shen eGuo, Yan eFan, Anne eWeigand, Juergen eBaudewig, Malek eBajbouj, Georg eNorthoff   +9 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A functional MRI study of altered spontaneous brain activity pattern in patients with congenital comitant strabismus using amplitude of low-frequency fluctuation

Neuropsychiatric Disease and Treatment, 2016
Gang Tan,1,2,* Xin Huang,1,3,* Ying Zhang,1 An-Hua Wu,2 Yu-Lin Zhong,1 Kai Wu,2 Fu-Qing Zhou,4 Yi Shao1 1Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute and Oculopathy ...
Tan G, Huang X, Zhang Y, Wu A, Zhong Y, Wu K, Zhou F, Shao Y   +7 more
doaj  

Fast Ca2+ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca2+ Waves of Inner Supporting Cells in the Developing Mouse Cochlea

Frontiers in Molecular Neuroscience, 2018
Before the onset of hearing, which occurs around postnatal day 12 (P12) in mice, inner hair cells (IHCs) of the immature cochlea generate sound-independent Ca2+ action potentials (APs), which stimulate the auditory pathway and guide maturation of ...
Tobias Eckrich, Kerstin Blum, Ivan Milenkovic, Jutta Engel   +3 more
doaj   +1 more source

Spontaneous Brain Activity Did Not Show the Effect of Violent Video Games on Aggression: A Resting-State fMRI Study

, 2018
A great many of empirical researches have proved that longtime exposure to violent video game can lead to a series of negative effects. Although research has focused on the neural basis of the correlation between violent video game and aggression, little
Liu, Fuqu, Pan, Wei, Gao, Xuemei, Fuqu Liu, Wei Pan, Chao Li, Xuemei Gao, Li, Chao, Shuo Shi, Shi, Shuo   +9 more
core   +1 more source