Results 101 to 110 of about 7,170,848 (305)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Wnts in adult brain: from synaptic plasticity to cognitive deficiencies

Frontiers in Cellular Neuroscience, 2013
During development of the central nervous system the Wnt signaling pathway has been implicated in a wide spectrum of physiological processes, including neuronal connectivity and synapse formation.
Carolina A. Oliva, Jessica Y. Vargas, Nibaldo C. Inestrosa   +2 more
doaj   +1 more source

SPONTANEOUS ACTIVITY AND CATECHOL AMINE EXCRETION

, 1964
No proportional correlation was found between average spontaneous running activity per week and excretion of adrenaline in white rats which were temporarily removed from the activity cages for 24-hour periods for the collection of urine.
L.-P. Dugal, Lorraine C. Smith
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Visually evoked spiking evolves while spontaneous ongoing dynamics persist

Frontiers in Systems Neuroscience, 2016
Neurons in the primary visual cortex spontaneously spike even when there are no visual stimuli. It is unknown whether the spiking evoked by visual stimuli is just a modification of the spontaneous ongoing cortical spiking dynamics or whether the ...
Raoul eHuys, Viktor K Jirsa, Ziauddin eDarokhan, Sonata eValentiniene, Per E Roland   +4 more
doaj   +1 more source

Neuronal Avalanches in Spontaneous Activity In Vivo

Journal of Neurophysiology, 2010
Many complex systems give rise to events that are clustered in space and time, thereby establishing a correlation structure that is governed by power law statistics. In the cortex, such clusters of activity, called “neuronal avalanches,” were recently found in local field potentials (LFPs) of spontaneous activity in acute cortex slices, slice cultures,
Gerald, Hahn, Thomas, Petermann, Martha N, Havenith, Shan, Yu, Wolf, Singer, Dietmar, Plenz, Danko, Nikolic   +6 more
openaire   +3 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Regulation of urothelial spontaneous contractile activity

, 2010
The bladder urothelium (urothelium plus suburothelium) plays an importantrole in regulating detrusor contractile activity but also exhibits a spontaneous contractile activity of its own.
Chess-Williams, Russ, Moro, Christian; id_orcid   +1 more
core   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Sustained increase of spontaneous input and spike transfer in the CA3-CA1 pathway following long term potentiation in vivo

Frontiers in Neural Circuits, 2012
Long term potentiation (LTP) is commonly used to study synaptic plasticity but the associated changes in the spontaneous activity of individual neurons or the computational properties of neural networks in vivo remain largely unclear.
Oscar eHerreras, Valeri eMakarov, Antonio eFernández-Ruiz   +2 more
doaj   +1 more source