Results 51 to 60 of about 803,284 (272)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Spontaneous Multi‐Interface Modulation for Enhancing Organic Transistor Performance via Self‐Generated Molecular Interlayers

Small Structures
The interfacial properties between source/drain electrodes and the active layer, as well as between the gate dielectric and the active layer, are critical determinants of the performance and operational stability of organic field‐effect transistors ...
Hansol Lee, Eun Ko, Taehoon Hwang, Yumin Kim, Jungyoon Seo, Jisu Park, Wentao Xu, Hyungju Ahn, Hwa Sung Lee   +8 more
doaj   +1 more source

Chondrogenic Differentiation of Porcine Skin-Derived Stem Cells with Different Characteristics of Spontaneous Adipocyte Formation

Journal of Animal Reproduction and Biotechnology, 2017
The purpose of this study is to confirm whether spontaneous adipocyte generation during chondrogenic induction culture affects the chondrogenic differentiation of porcine skin-derived stem cells (pSSCs).
Hyo-Kyung Bae, Bae-Dong Jung, Seunghyung Lee, Choon-Keun Park, Boo-Keun Yang, Hee-Tae Cheong   +5 more
doaj   +1 more source

Possibility of spontaneous CP violation in the nonminimal supersymmetric standard model with two neutral Higgs singlets

, 2002
A supersymmetric standard model with two Higgs doublets and two Higgs singlets is investigated if it can accommodate the possibility of spontaneous CP violation.
A. Pilaftsis, A. Pilaftsis, A. Pilaftsis, A. Pomarol, A. Stephan, A.G. Akeroyd, C. Panagiotakopoulos, D. Son, D.A. Demir, F. Franke, F. Franke, F. Wilczek, G.L. Kane, H.P. Nilles, J. Ellis, J.C. Romão, J.F. Gunion, J.H. Christenson, J.I. Kamoshita, J.R. Espinosa, J.R. Espinosa, J.R. Espinosa, K.S. Babu, M. Acciarri, M. Carena, M. Carena, M. Drees, M. Drees, M. Kobayashi, M. Masip, M. Masip, M. Masip, M. Matsuda, N. Cabibbo, N. Haba, N. Haba, N. Haba, N. Maekawa, O. Lebedev, O. Lebedev, P. Binétruy, P.N. Pandita, R. Barate, R.D. Peccei, R.D. Peccei, S. Coleman, S. Glashow, S. K. Oh, S. W. Ham, S. Weinberg, S. Weinberg, S. Weinberg, S. Weinberg, S.F. King, S.W. Ham, S.W. Ham, S.W. Ham, S.W. Ham, S.W. Ham, S.Y. Choi, S.Y. Choi, T. Elliott, T. Ibrahim, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, Y. Okada   +72 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Spontaneous Nambu-Goldstone Currents Generation Driven by Mismatch

, 2006
We review recent progress of understanding and resolving instabilities driven by mismatch between the Fermi surfaces of the pairing quarks in 2-flavor color superconductor.
Huang, Mei
core   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria

Acta Dermato-Venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predictors
Yingyi Li, Rui Peng, Jingwen Xue, Yi Zhao   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source