Results 111 to 120 of about 6,486,745 (293)

Long-lasting pain-related behaviors in mouse chronic cystitis model induced by a single intravesical injection of hydrogen peroxide

open access: yesJournal of Pharmacological Sciences, 2015
We previously established a long-lasting cystitis model by an intravesical injection of hydrogen peroxide (H2O2) into mice. In this study, we assessed the pain-related behaviors in the cystitis model.
Koji Dogishi   +5 more
doaj   +1 more source

Locomotor Behavioral Assessments [online video]

open access: yes, 2015
What questions should you ask when deciding on a behavioral/locomotor test for rodents? This talk covers how to determine which locomotor assay is best for your research, e.g. spontaneous activity, beam walking, rotorod, etc.
Muldoon, Pretal
core  

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

Spontaneous night and day locomotor activity.

open access: yes, 2013
Data were recorded during 5 consecutive 24 h periods (expressed in arbitrary units of locomotor activity). Values are means ± SEM, n = 6 in each dietary group.
Jean-Marc Alessandri (350281)   +6 more
core   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

open access: yesAdvanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai   +10 more
wiley   +1 more source

Development and characterization of an equine behaviour chamber and the effects of amitraz and detomidine on spontaneous locomotor activity

open access: yes, 1997
This report describes the development of a behaviour chamber and the validation of the chamber to measure locomotor activity of a horse, Locomotor activity was detected by four Mini-beam sensors and recorded on a data logger every 5 min for 22 h.
QueirozNeto, A.   +9 more
core   +1 more source

Active Oscillations of Elastic Membranes Arising from the Coupling with a Catalytic Reaction

open access: yesAdvanced Science, EarlyView.
Coupling an elastic membrane to a catalytic reaction produces active oscillations that self‐sustain for hours: the membrane cyclically inflates and deflates as the reaction spontaneously activates and deactivates, without external power. Energy release is directly embodied in the oscillation dynamics, opening elasto‐chemical strategies for the physical
Alberto Comoretto   +5 more
wiley   +1 more source

Effect of electroacupuncture on expression of CREB and its ability to bind to synaptic proteins in amygdala and hippocampus of rats with post-traumatic stress disorder

open access: yes针刺研究, 2020
Objective To observe the effect of electroacupuncture(EA) on the expression of cAMP-response element binding protein(CREB, a key protein for BDNF-TrkB signaling) and it's blinding ability to synaptic key protein in the amygdala and hippocampus of rats ...
LI Mi   +5 more
doaj   +2 more sources

Locomotor exercise and circadian rhythms in mammals [PDF]

open access: yes
The timing of locomotor activity is a major rhythmic output of the mammalian circadian system but both spontaneous and induced exercise can also themselves impact on circadian rhythms across levels of organisation and in multiple tissues, including both ...
Hughes, ATL
core   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

open access: yesAdvanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park   +16 more
wiley   +1 more source

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