Results 91 to 100 of about 6,486,745 (293)
, 2013 Evaluation of spontaneous activity using BBB locomotor scale shows that treatment of rats at 20 minutes after lesion with AM281, AM630 or AM281/AM630 impairs recovery.
Angel Arevalo-Martin (298990) +6 more
core +1 more source
Advanced Science, EarlyView.Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
, 2013 Data of control (CTL), caloric restricted (CR) or resveratrol supplemented (RSV) mouse lemurs after 18 months of dietary interventions are reported. Figure 5A represents physical performances of the animals in a jump task (expressed in cm, with n = 9 CTL,
Julia Marchal (174481) +4 more
core +1 more source
Abstract Representation of Movement Parameters in Basal Ganglia Output
Advanced Science, EarlyView.The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero +3 more
wiley +1 more source
Abnormal brain functional activity and changes in c-Fos expression of propofol dependence in rats
Brain Research BulletinPropofol demonstrates dependence at subclinical anesthetic doses, however, the underlying neural mechanisms remain unclear. In this study, we established a self-administration model of propofol in Sprague-Dawley (SD) rats, used a combination of the ...
Zelin Zhuang +12 more
doaj +1 more source
Changes in 24 h Rhythmicity of Spontaneous Locomotor Activity in the Triple Transgenic Mouse for Alzheimer's Disease (3xTg-AD) in a Jet Lag Protocol: Correlations with Retinal Sensitivity. [PDF]
J Circadian Rhythms, 2021 González-Luna IA +6 more
europepmc +1 more source
Effect of lamotrigine alone or in combination with conventional antiepileptic drugs on locomotor activity in mice [PDF]
, 2004 OBJECTIVE: To evaluate the acute adverse effects with respect to exploratory and spontaneous locomotor activity of mice produced by lamotrigine (LTG) alone or in combination with conventional antiepileptic drugs (AEDs) such as valproate ...
J.J. Luszczki
core
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
Lack of Effects of Anabolic-Androgenic Steroids on Locomotor Activity in Intact Male Mice
, 1999 Anabolic-androgenic steroid abusers have reported hyperactivity euphoria, and decreased fatigue, among other behavioral effects. It has been suggested that the effects of these substances on the central nervous system are similar to those of ...
V. M. Simón +3 more
core +1 more source
Chronic electromyographic analysis of circadian locomotor activity in crayfish [PDF]
, 2013 Animals generally exhibit circadian rhythms of locomotor activity. They initiate locomotor behavior not only reflexively in response to external stimuli but also spontaneously in the absence of any specific stimulus.
Tomina, Yusuke +3 more
core +1 more source