Results 181 to 190 of about 6,486,745 (293)

Chronic High‐Dose Ketamine Fails to Induce a Cystitis‐Like Phenotype in Mice Despite High Urinary Metabolite Levels

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Ketamine‑induced cystitis (KIC) is a severe complication of chronic ketamine misuse, yet the underlying mechanisms remain poorly understood. Established rodent models have demonstrated variable changes in voiding behavior and bladder histology, without exploring the sensory mechanisms underlying altered voiding and pain at all. This study
Jill Dewez   +11 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Continued post-weaning social isolation is associated with persistent, sex-specific changes in sociability and social interaction dynamics in mice. [PDF]

open access: yesPLoS One
Yamamuro K   +9 more
europepmc   +1 more source

Hinokitiol Promotes Neural Repair After Spinal Cord Injury by Reprogramming Microglial Inflammatory and Redox Responses

open access: yesPhytotherapy Research, EarlyView.
Schematic illustration showing that Hinokitiol promotes neural repair after spinal cord injury by activating the Keap1/Nrf2/HO‐1 signaling pathway and reprogramming microglial inflammatory‐redox responses. ABSTRACT Secondary neuroinflammation and oxidative stress, driven partly by maladaptive microglial activation, limit recovery after spinal cord ...
Wenhao Zhang   +10 more
wiley   +1 more source

Salidroside Alleviates AlCl3/D‐galactose‐Induced Alzheimer's Disease‐Like Mice Neuronal Damage and Synaptic Dysfunction Through Keap1/Nrf2/GSH Signaling Axis

open access: yesPhytotherapy Research, EarlyView.
Salidroside alleviates AlCl3/D‐galactose‐induced neuronal injury and synaptic dysfunction in AD‐like mice via regulation of the Keap1/Nrf2/GSH signaling axis. ABSTRACT Alzheimer's disease (AD) is associated with glutathione (GSH) depletion and redox imbalance in the brain, contributing to hippocampal neuronal damage and synaptic dysfunction and ...
Heying Cui   +9 more
wiley   +1 more source

Linear System Identification and Control of a Low‐Cost High‐Performance Omnidirectional Marine Surface Vehicle for Swarming Applications

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Marine operations traditionally rely on human intervention, a costly and disruptive method. Autonomous surface vehicles (ASVs) offer a powerful alternative, capable of operating autonomously, for extended periods, and with various sensors for various missions.
Ayman El Qemmah   +4 more
wiley   +1 more source

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