Results 41 to 50 of about 3,537,154 (243)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Optical Potts machine through networks of three-photon down-conversion oscillators

open access: yesNanophotonics, 2020
In recent years, there has been a growing interest in optical simulation of lattice spin models for applications in unconventional computing. Here, we propose optical implementation of a three-state Potts spin model by using networks of coupled ...
Honari-Latifpour Mostafa   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Manipulating Orbital Angular Momentum Entanglement in Three-Dimensional Spiral Nonlinear Photonic Crystals

open access: yesPhotonics, 2022
We propose and theoretically investigate two-photon orbital angular momentum (OAM) correlation through spontaneous parameter down-conversion (SPDC) processes in three-dimensional (3D) spiral nonlinear photonic crystals (NPCs).
Qian Yu   +8 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Steps towards the experimental realization of surface plasmon polariton enhanced spontaneous parametric down-conversion

open access: yes, 2018
The realization of efficient and miniature source of entangled photon pairs stills remains a challenge. In this work, we experimentally studied the possibility to enhance the process of spontaneous parametric down-conversion by surface plasmon polaritons.
Ardi Loot (6065270)   +4 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Local Realistic Interpretation of Entangled Photon Pairs in the Weyl-Wigner Formalism

open access: yesFrontiers in Physics, 2020
A polarization correlation experiment with two maximally entangled photons created by spontaneous parametric down-conversion is studied in the Weyl-Wigner formalism, that reproduces the quantum predictions.
Emilio Santos
doaj   +1 more source

Interference fringes in a nonlinear Michelson interferometer based on spontaneous parametric down-conversion

open access: yes, 2021
Quantum nonlinear interferometers (QNIs) can measure the infrared physical quantities of a sample by detecting visible photons. A QNI with Michelson geometry based on the spontaneous parametric down-conversion in a second-order nonlinear crystal is ...
Liu-Long Wang (11424799)   +9 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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