Results 91 to 100 of about 11,396 (179)

The new variant of the Creutzfeldt-Jakob disease accounts for no relative increase of the Creutzfeldt-Jakob disease mortality rate in the United Kingdom; this fits ill with the new variant being the consequence of consumption of food infected with the agent of Bovine Spongiform Encephalopathy

BMC Public Health, 2003
Background A new variant of Creutzfeldt-Jakob disease was described in the United Kingdom. It is often claimed that it is caused by consumption of food infected with the agent of bovine spongiform encephalopathy.
Hénaut Alain, Laprevotte Ivan
doaj   +1 more source

Neuroimagen estructural y funcional en las enfermedades priónicas humanas [PDF]

, 2011
INTRODUCTION: Prion diseases are neurodegenerative disorders resulting from the accumulation of a misfolded isoform of the cellular prion protein (PrPc). They can occur as acquired, sporadic or hereditary forms. Although prion diseases show a wide range
Arbizu, J. (Javier), Carmona-Abellan, M. (M.), Dominguez-Prado, I. (Inés), Luquin, M.R. (María Rosario), Ortega-Cubero, S. (Sara), Pagola, I. (I.), Riverol, M. (Mario)   +6 more
core  

Cross currents in protein misfolding disorders: interactions and therapy. [PDF]

, 2009
Protein Misfolding Disorders (PMDs) are a group of diseases characterized by the accumulation of abnormally folded proteins. Despite the wide range of proteins and tissues involved, PMDs share similar molecular and pathogenic mechanisms.
Green, Kristi M, Morales, Rodrigo, Soto, Claudio   +2 more
core   +1 more source

Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process

NeuroImage: Clinical, 2019
Prion diseases are a group of rare neurodegenerative conditions characterised by a high rate of progression and highly heterogeneous phenotypes. Whilst the most common form of prion disease occurs sporadically (sporadic Creutzfeldt–Jakob disease, sCJD ...
Liane S. Canas, Carole H. Sudre, Enrico De Vita, Akin Nihat, Tze How Mok, Catherine F. Slattery, Ross W. Paterson, Alexander J.M. Foulkes, Harpreet Hyare, M. Jorge Cardoso, John Thornton, Jonathan M. Schott, Frederik Barkhof, John Collinge, Sébastien Ourselin, Simon Mead, Marc Modat   +16 more
doaj   +1 more source

Diagnosing Sporadic Creutzfeldt-Jakob Disease by the Detection of Abnormal Prion Protein in Patient Urine [PDF]

, 2016
IMPORTANCE: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disorder associated with the accumulation of infectious abnormal prion protein through a mechanism of templated misfolding.
Collinge, J, Fox, NC, Jackson, GS, Jones, S, Luk, C, Mead, S, Mok, TH, Thomas, C   +7 more
core   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A., Jacobs, J.G., Keulen, L.J.M., van, Langeveld, J.P.M., Sauer, M., Tang, Y.   +5 more
core   +2 more sources

The most problematic symptoms of prion disease - an analysis of carer experiences [PDF]

, 2019
Objectives: Prion diseases are rare dementias that most commonly occur sporadically, but can be inherited or acquired, and for which there is no cure.
Collinge, John, Ford, Liz, Gorham, Michele, Mead, Simon, Robinson, Kathy, Rudge, Peter   +5 more
core   +2 more sources

Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare

Genome Medicine, 2018
Editorial summary Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery.
Akin Nihat, Simon Mead
doaj   +1 more source

Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein [PDF]

, 2017
The epizootic prion disease of cattle, bovine spongiform encephalopathy (BSE), causes variant Creutzfeldt-Jakob disease (vCJD) in humans following dietary exposure.
Asante, EA, Bellworthy, SJ, Brandner, S, Brock, L, Collinge, J, Hope, J, Joiner, S, Linehan, JM, Simmons, MM, Wadsworth, JDF   +9 more
core   +1 more source

Creutzfeldt–Jakob disease‐like imaging in valosin‐containing protein D395G mutation

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Ryota Kobayashi, Masafumi Kanoto, Shinobu Kawakatsu, Akihito Suzuki   +3 more
wiley   +1 more source