Results 91 to 100 of about 5,104,410 (171)
Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]
Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Taratuto, A. +26 more
core
All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD [PDF]
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the ...
Smith, Antony +58 more
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Detection of Creutzfeldt-Jakob disease prions in skin: implications for healthcare
Editorial summary Evidence has recently been reported of prion seeding activity in skin tissue from patients with sporadic Creutzfeldt-Jakob disease (sCJD). This is relevant information for infection control measures during surgery.
Akin Nihat, Simon Mead
doaj +1 more source
Dental treatment and risk of variant CJD - a case control study [PDF]
Objective: Knowledge of risk factors for variant CJD (vCJD) remains limited, but transmission of prion proteins via re-useable medical devices, including dental instruments, or enhanced susceptibility following trauma to the oral cavity is a concern ...
Everington, D. +11 more
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Differentiation of Prions from L-type BSE versus Sporadic Creutzfeldt-Jakob Disease
We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein–transgenic mouse line and isolated distinct prion
Simon Nicot +5 more
doaj +1 more source
A novel protective prion protein variant that colocalizes with kuru exposure. [PDF]
BACKGROUND: Kuru is a devastating epidemic prion disease that affected a highly restricted geographic area of the Papua New Guinea highlands; at its peak, it predominantly affected adult women and children of both sexes.
Whittaker, John +26 more
core +1 more source
Serial EEG findings in sporadic and iatrogenic Creutzfeldt-Jakob disease.
OBJECTIVE To study temporal and spatial development of EEG patterns in sporadic and iatrogenic Creutzfeldt-Jakob disease patients. METHODS Temporal and spatial development of EEG patterns in 4 patients with sporadic Creutzfeldt-Jakob disease and 2 ...
Wieser HG +6 more
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Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease.
BACKGROUND: The prevalence and characteristics of sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease (sCJD) are poorly understood. METHODS: Seven consecutive patients with definite sCJD underwent a systematic assessment of sleep-wake ...
Achermann, P +21 more
core +1 more source
Creutzfeldt-Jakob disease (CJD) can be iatrogenically transmitted during transplants, grafts and transfusions from CJD infected donors and also contaminated surgical instruments.
Secker, Thomas
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