Results 41 to 50 of about 418,438 (292)

Thioflavin-T does not report on electrochemical potential and memory of dormant or germinating bacterial spores

mBio, 2023
Bacterial spores are metabolically dormant, resistant to microbicides, and vectors of food spoilage and diseases, while germinated spores are easy to kill. Consequently, understanding germination mechanisms may facilitate the development of “germinate-to-
Yong-qing Li, Lin He, Makunda Aryal, James Wicander, George Korza, Peter Setlow   +5 more
doaj   +1 more source

Arginine dephosphorylation propels spore germination in bacteria

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Dormant bacterial spores can survive long periods of time, withstanding extreme conditions, but can rapidly resume a vegetative life form once nutrients become accessible.
B. Zhou, Maja Šemanjski, Natalie Orlovetskie, S. Bhattacharya, Sima Alon, Liron Argaman, Nayef Jarrous, Yan Zhang, B. Maček, L. Sinai, Sigal Ben-Yehuda   +10 more
semanticscholar   +1 more source

Inhibition of spore germination, growth, and toxin activity of clinically relevant C. difficile strains by gut microbiota derived secondary bile acids

Anaerobe, 2017
The changing epidemiology of Clostridium difficile infection over the past decades presents a significant challenge in the management of C. difficile associated diseases.
R. Thanissery, Jenessa A. Winston, C. Theriot   +2 more
semanticscholar   +1 more source

Comparison of sporulation and germination conditions for Clostridium perfringens type A and G strains

Frontiers in Microbiology, 2023
Clostridium perfringens is a spore forming, anaerobic, Gram-positive bacterium that causes a range of diseases in humans and animals. C. perfringens forms spores, structures that are derived from the vegetative cell under conditions of nutrient ...
Marc Liggins, Norma Ramírez Ramírez, Norma Ramírez Ramírez, Ernesto Abel-Santos   +3 more
doaj   +1 more source

Effects of Different Bacteriostats on the Dynamic Germination of Clostridium perfringens Spores

Foods, 2023
Bacteriostats, as chemical substances that inhibit bacterial growth, are widely used in the sterilization process; however, their effects on spindle spores are unclear.
Dong Liang, Shengnan Liu, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Lingxia Sun, Yangyang Ma, Gaiming Zhao   +7 more
doaj   +1 more source

Updates to Clostridium difficile Spore Germination

Journal of Bacteriology, 2018
Germination of Clostridium difficile spores is a crucial early requirement for colonization of the gastrointestinal tract. Likewise, C. difficile cannot cause disease pathologies unless its spores germinate into metabolically active, toxin-producing ...
T. Kochan, M. Foley, Michelle S Shoshiev, Madeline J. Somers, Paul E. Carlson, P. Hanna   +5 more
semanticscholar   +1 more source

Intracellular membranes of bacterial endospores are reservoirs for spore core membrane expansion during spore germination

Scientific Reports, 2018
Bacterial endospores are formed by certain bacteria, such as Bacillus subtilis or the pathogenic Bacillus anthracis and Clostridioides difficile, to allow survival in environmental conditions which are lethal to vegetative bacteria.
M. Laue, Hong-Mei Han, Christin Dittmann, P. Setlow   +3 more
semanticscholar   +1 more source

Observation's on the germination of Endogone spores

Transactions of the British Mycological Society, 1976
Although reliable germination of Endogone spores has previously been difficult to achieve, it was possible to obtain greater than 90% yields of germinated E. mosseae Nicolson & Gerdemann spores on distilled water agar. Zinc and manganese, at the concentrations present in many commercially available agars could completely inhibit spore germination ...
Hepper, C. M., Smith, G. A.
openaire   +1 more source

Integrative Analysis of Proteome and Transcriptome Dynamics during Bacillus subtilis Spore Revival

mSphere, 2020
Bacillus subtilis spores can reactivate their metabolism through germination upon contact with germinants and can develop into vegetative cells upon outgrowth.
Bhagyashree Swarge, Wishwas Abhyankar, Martijs Jonker, Huub Hoefsloot, Gertjan Kramer, Peter Setlow, Stanley Brul, Leo J. de Koning   +7 more
doaj   +3 more sources

Germinant Synergy Facilitates Clostridium difficile Spore Germination under Physiological Conditions

Msphere, 2018
Clostridium difficile is an anaerobic spore-forming human pathogen that is the leading cause of nosocomial infectious diarrhea worldwide. Germination of infectious spores is the first step in the development of a C.
T. Kochan, Michelle S Shoshiev, Jessica L. Hastie, Madeline J. Somers, Yael M. Plotnick, Daniela F. Gutierrez-Munoz, Elissa D. Foss, Alyxandria M. Schubert, A. D. Smith, Sally K. Zimmerman, Paul E. Carlson, P. Hanna   +11 more
semanticscholar   +1 more source