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Clostridioides difficile spores produced during infection are important for the recurrence of the disease. Here, we show that C. difficile spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin-α5β1 and vitronectin-αvβ1 ...
Pablo Castro-Córdova+10 more
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Auranofin and Baicalin Inhibit Clostridioides difficile Growth and Sporulation: An In vitro Study
Clostridioides difficile is a principal cause of hospital-acquired gastrointestinal infections, with sporulation and toxin production being key determinants in the disease pathogenesis.
Lamiaa A. Madkour
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Bacillus cereus spores, like most Bacillus spores, can survive for years and germinate when their surroundings become suitable, and germination proteins play an important role in the initiation of germination.
Yan Wang+5 more
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Short Communication: Efficacy of Two Commercial Disinfectants on Paenibacillus larvae Spores
Paenibacillus larvae is a spore-forming bacterium causing American foulbrood (AFB) in honey bee larvae. The remains of a diseased larva contains billions of extremely resilient P. larvae spores viable for decades.
Joseph Kiriamburi+4 more
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Ebselen, a reactive organoselenium compound, was shown to inhibit toxins TcdA and TcdB by covalently binding to their cysteine protease domains. It was suggested that ebselen lacked antimicrobial activity against Clostridioides difficile.
Ravi K. R. Marreddy+4 more
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Alicyclobacillus acidoterrestris (A. acidoterrestris), a spore-forming bacterium, has become a main challenge and concern for the juices and acid beverage industry across the world due to its thermo-acidophilic characteristic. Thymoquinone (TQ) is one of
Qiuxia Fan+15 more
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UV-B absorbing pigments in spores: biochemical responses to shade in a high-latitude birch forest and implications for sporopollenin-based proxies of past environmental change [PDF]
Current attempts to develop a proxy for Earth's surface ultraviolet-B (UV-B) flux focus on the organic chemistry of pollen and spores because their constituent biopolymer, sporopollenin, contains UV-B absorbing pigments whose relative abundance may ...
Terry V. Callaghan+8 more
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Bacillus spores: a review of their properties and inactivation processing technologies
Many factors determine the resistance properties of a Bacillus spore to heat, chemical and physical processing, including thick proteinaceous coats, peptidoglycan cortex and low water content, high levels of dipicolinic acid (DPA), and divalent cations ...
W. Cho, M. Chung
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Food and water security issues in Russia II: Water security in general population of Russian Arctic, Siberia and Far East, 2000–2011 [PDF]
Background . Poor state of water supply systems, shortage of water purification facilities and disinfection systems, low quality of drinking water generally in Russia and particularly in the regions of the Russian Arctic, Siberia and Far East have been ...
Alexey A. Dudarev+9 more
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Aspergillus niger Spores Are Highly Resistant to Space Radiation
The filamentous fungus Aspergillus niger is one of the main contaminants of the International Space Station (ISS). It forms highly pigmented, airborne spores that have thick cell walls and low metabolic activity, enabling them to withstand harsh ...
M. Cortesão+6 more
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