Results 21 to 30 of about 1,810 (161)

Development of a Versatile Toolbox for Genetic Manipulation of <i>Sporothrix brasiliensis</i>. [PDF]

Microbiol Spectr, 2023
Sporotrichosis is the most prevalent subcutaneous mycosis worldwide and has recently become a public health concern. Although immunocompetent hosts are also prone to sporotrichosis, immunodeficient hosts often develop a more severe and disseminated form of disease.
Tavares M, Sousa-Filho JC, Machado IA, Gonçales RA, Antunes D, Mendes-Frias A, Silvestre R, Carvalho A, Torrado E, Cunha C, Rodrigues F.   +10 more
europepmc   +3 more sources

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells. [PDF]

Infect Drug Resist, 2023
Sporotrichosis is a mycosis frequently caused by Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa. The cell wall is a species-specific fungal structure with a direct role in activating the host's immune response. The current knowledge about anti-Sporothrix immunity comes from studies using S. schenckii or S. brasiliensis and murine
Gómez-Gaviria M, Martínez-Duncker I, García-Carnero LC, Mora-Montes HM.   +3 more
europepmc   +4 more sources

Beyond Domestic Cats: Environmental Detection of Sporothrix brasiliensis DNA in a Hyperendemic Area of Sporotrichosis in Rio de Janeiro State, Brazil

Journal of Fungi, 2022
In Brazil, sporotrichosis has transitioned from a rural to urban disease, driven by a shift in the initiation of infection from the accidental inoculation of organic matter to the traumatic implantation of the fungus by cats.
Fernando Almeida-Silva, Vanessa Brito de Souza Rabello, Bruno de Souza Scramignon-Costa, Rosely Maria Zancopé-Oliveira, Priscila Marques de Macedo, Rodrigo Almeida-Paes   +5 more
doaj   +1 more source

Differential Recognition of Clinically Relevant Sporothrix Species by Human Granulocytes

Journal of Fungi, 2023
Sporotrichosis is a cutaneous mycosis that affects humans and animals and has a worldwide distribution. This infection is mainly caused by Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa.
Ana K. Galván-Hernández, Manuela Gómez-Gaviria, Iván Martínez-Duncker, José A. Martínez-Álvarez, Héctor M. Mora-Montes   +4 more
doaj   +1 more source

Disseminated sporotrichosis caused by <i>Sporothrix brasiliensis</i> with testicular involvement. [PDF]

Med Mycol Case Rep
Sporotrichosis is a growing public health concern especially due Sporothrix brasiliensis. We report a case of disseminated sporotrichosis involving the meninges, lungs, and testicles in a 35-year-old homeless man from Curitiba, Brazil. Fungal culture, histopathology, and molecular identification confirmed S. brasiliensis infection.
Cognialli RCR, Taborda MH, Carneiro BH, do Prado CM, Wolski MM, Breda GL, Spruijtenburg B, Vicente VA, Meijer EFJ, de Queiroz-Telles F.   +9 more
europepmc   +6 more sources

An anti-adhesive peptide found in extracellular vesicles from <i>Sporothrix brasiliensis</i> and <i>Sporothrix schenckii</i>. [PDF]

Cell Surf
Sporothrix brasiliensis and Sporothrix schenckii are major causative agents of sporotrichosis, a neglected fungal disease with growing public health relevance. These pathogens release extracellular vesicles (EVs) that contribute to host-pathogen interactions, yet their small molecule content remains unexplored.
de Souza CM, Sensato NA, Reis FCG, Pinheiro MSS, Santos MDM, Camillo-Andrade AC, Shigunov P, de Oliveira HC, Carvalho PC, Fill TP, Rodrigues ML.   +10 more
europepmc   +3 more sources

CRISPR-based tools for targeted genetic manipulation in pathogenic Sporothrix species

Microbiology Spectrum, 2023
Sporothrix brasiliensis is an emerging fungal pathogen frequently associated with zoonotic transmission of sporotrichosis by contaminated cats. Within 25 years, the disease has spread not only throughout Brazil but now to neighboring countries in Latin ...
Remi Hatinguais, Ian Leaves, Gordon D. Brown, Alistair J. P. Brown, Matthias Brock, Roberta Peres da Silva   +5 more
doaj   +1 more source

Phylogenetic analysis reveals a high prevalence of Sporothrix brasiliensis in feline sporotrichosis outbreaks. [PDF]

PLoS Neglected Tropical Diseases, 2013
Sporothrix schenckii, previously assumed to be the sole agent of human and animal sporotrichosis, is in fact a species complex. Recently recognized taxa include S. brasiliensis, S. globosa, S. mexicana, and S. luriei, in addition to S.
Anderson Messias Rodrigues, Marcus de Melo Teixeira, G Sybren de Hoog, Tânia Maria Pacheco Schubach, Sandro Antonio Pereira, Geisa Ferreira Fernandes, Leila Maria Lopes Bezerra, Maria Sueli Felipe, Zoilo Pires de Camargo   +8 more
doaj   +1 more source

Proteins Potentially Involved in Immune Evasion Strategies in Sporothrix brasiliensis Elucidated by Ultra-High-Resolution Mass Spectrometry

mSphere, 2018
Sporothrix brasiliensis is the prevalent agent of a large zoonotic outbreak in Brazil. With the involvement of several thousands of cases, this is the largest cohort of human and animal sporotrichosis on record in the world.
Luana Rossato, Leandro Ferreira Moreno, Azadeh Jamalian, Benjamin Stielow, Sandro Rogério de Almeida, Sybren de Hoog, Joanna Freeke   +6 more
doaj   +1 more source

Differential Recognition of Clinically Relevant Sporothrix Species by Human Mononuclear Cells

Journal of Fungi, 2023
Sporotrichosis is a human and animal fungal infection distributed worldwide that is caused by the thermodimorphic species of the Sporothrix pathogenic clade, which includes Sporothrix brasiliensis, Sporothrix schenckii, and Sporothrix globosa.
Laura C. García-Carnero, Iván Martínez-Duncker, Manuela Gómez-Gaviria, Héctor M. Mora-Montes   +3 more
doaj   +1 more source