Results 51 to 60 of about 1,775 (147)

Melanins Protect Sporothrix brasiliensis and Sporothrix schenckii from the Antifungal Effects of Terbinafine

PLOS ONE, 2016
Terbinafine is a recommended therapeutic alternative for patients with sporotrichosis who cannot use itraconazole due to drug interactions or side effects. Melanins are involved in resistance to antifungal drugs and Sporothrix species produce three different types of melanin.
Rodrigo Almeida-Paes, Maria Helena Galdino Figueiredo-Carvalho, Fábio Brito-Santos, Fernando Almeida-Silva, Manoel Marques Evangelista Oliveira, Rosely Maria Zancopé-Oliveira   +5 more
openaire   +4 more sources

Sporothrix brasiliensis produces the highest levels of oxidative stress in a murine model among the species of the Sporothrix schenckii complex

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: We compared indicators of oxidative stress in the tissue of mice infected with strains from Sporothrix schenckii complex. METHODS: Mice were inoculated with Sporothrix brasiliensis, Sporothrix schenckii sensu stricto, Sporothrix globosa,
Débora Nunes Mario, Larissa Finger Schaffer, Luis Ricardo Peroza, Francielli Pantella Kunz de Jesus, Laura Bedin Denardi, Roselei Fachinetto, Sydney Hartz Alves   +6 more
doaj   +1 more source

Proteomics-Based Characterization of the Humoral Immune Response in Sporotrichosis: Toward Discovery of Potential Diagnostic and Vaccine Antigens. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Sporothrix schenckii and associated species are agents of human and animal sporotrichosis that cause large sapronoses and zoonoses worldwide.
Anderson Messias Rodrigues, Geisa Ferreira Fernandes, Leticia Mendes Araujo, Paula Portella Della Terra, Priscila Oliveira dos Santos, Sandro Antonio Pereira, Tânia Maria Pacheco Schubach, Eva Burger, Leila Maria Lopes-Bezerra, Zoilo Pires de Camargo   +9 more
doaj   +1 more source

Esporotricosis por Sporothrix brasiliensis

, 2023
Fil: Cuestas, María Luján. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina.
Bava, Javier, Cuestas, Luján, Etchecopaz, Alejandro   +2 more
openaire   +2 more sources

A case of disseminated sporotrichosis caused by Sporothrix brasiliensis

Medical Mycology Case Reports, 2018
This paper presents a case of disseminated sporotrichosis in a 13-year-old female, originating from a rural area in Minas Gerais state, Brazil. The patient was hospitalized in Santa Casa hospital of Belo Horizonte, with hyporexia, prostration, fever and disseminated ulcerative lesions, besides anemia, leucopenia and sepsis of probable cutaneous focus ...
Fernandes, Blenda, Caligiorne, Rachel Basques, Coutinho, Dayana Monteiro, Gomes, Renata R., Rocha-Silva, Fabiana, Machado, Amanda Sanchez, Santrer, Emanoelle Fernandes Rutren La, Assunção, Claudia Barbosa, Guimarães, Cássio Ferreira, Laborne, Maria Silvia, Nunes, Mauricio Buzelin, Vicente, Vania A., de Hoog, Sybren   +12 more
openaire   +3 more sources

Synthesis and Identification of Pentathiepin-Based Inhibitors of Sporothrix brasiliensis [PDF]

Antibiotics, 2019
Sporothrix brasiliensis is the causative agent of zoonotic sporotrichosis in Brazil and is currently referred to as the most virulent species among those of clinical importance within the genus. Sporotrichosis is an emergent disease that has come to the forefront over two decades with a recent hot spot of sporotrichosis infection emerging in the state ...
Christopher R. M. Asquith, Ana C. S. Machado, Luisa H. M. de Miranda, Lidia S. Konstantinova, Rodrigo Almeida-Paes, Oleg A. Rakitin, Sandro A. Pereira   +6 more
openaire   +2 more sources

Phylogenetic analysis of Sporothrix brasiliensis isolated from feline sporotrichosis on São Luís Island, Maranhão, Brazil [PDF]

Pesquisa Veterinária Brasileira
: Sporotrichosis is a zoonotic cutaneous mycosis caused by saprophytic fungi of the Sporothrix, affecting cats, horses, dogs, and humans. This study aimed to evaluate sporotrichosis in cats clinically and to phenotypically characterize and molecularly ...
Allana F. Barros, Juliana S. Vitor, Yanara R.C.M. Esposito, Nayara S. Oliveira, Ellainy M.C. Silva, Ilka M.R. de Souza, Thiago A. de Melo, Elmary C. Fraga, Alcina V.C. Neta, Fábio H.E. de Andrade, Fernando Almeida-Souza, Larissa S.S. Ribeiro, Ana Lucia Abreu-Silva   +12 more
doaj   +1 more source

Advances in the Design of Photoactivatable Metallodrugs: Excited State Metallomics

Angewandte Chemie, Volume 137, Issue 9, February 24, 2025.
Fasten your seat belt! Choose lightning‐speed, photoactivated journeys for complexes by selecting the metal, its oxidation state, ligands and geometry. Track complexes through excited singlet (S) states, intersystem crossing (ISC) to triplet (T) states, energy/charge‐transfer, luminescence, ligand substitutions and redox reactions.
Huayun Shi, Rafael C. Marchi, Peter J. Sadler   +2 more
wiley   +2 more sources

Genome-wide mapping using new AFLP markers to explore intraspecific variation among pathogenic Sporothrix species.

PLoS Neglected Tropical Diseases, 2020
Sporotrichosis is a chronic subcutaneous mycosis caused by Sporothrix species, of which the main aetiological agents are S. brasiliensis, S. schenckii, and S. globosa.
Jamile Ambrósio de Carvalho, Ferry Hagen, Matthew C Fisher, Zoilo Pires de Camargo, Anderson Messias Rodrigues   +4 more
doaj   +1 more source

Emerging Frontiers in Clinical Mycology: Innovations, Insights, and Impacts

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT The Mycoses Study Group Education and Research Consortium (MSGERC)—a group comprising clinicians, researchers, patients, and industry partners—meets every 2 years to review the most significant challenges facing the clinical mycology community and plan research, education, and advocacy strategies to prevent fungal infections and improve ...
A. Apostolopoulou, A. G. Stewart, H. Yoon, J. M. Steinbrink, D. Z. P. Friedman, L. Ostrosky‐Zeichner, I. S. Schwartz, on behalf of the Mycoses Study Group Education and Research Consortium (MSGERC)   +7 more
wiley   +1 more source