Results 21 to 30 of about 6,535 (217)

Chitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis. [PDF]

BMC Microbiol, 2021
Fungal cell wall polysaccharides maintain the integrity of fungi and interact with host immune cells. The immunomodulation of fungal polysaccharides has been demonstrated in previous studies. However, the effect of chitin-rich heteroglycan extracted from
Huang L, Zhang J, Du W, Liang Z, Li M, Wu R, Chen S, Hu X, Huang H.   +8 more
europepmc   +2 more sources

Identification of two potential inhibitors of Sporothrix brasiliensis and Sporothrix schenckii in the Pathogen Box collection. [PDF]

PLoS One, 2020
Sporotrichosis is a neglected endemic mycosis with a high incidence in Latin America, mainly in Brazil. Sporothrix schenckii is the most frequent species in Latin America, whereas Sporothrix brasiliensis is the predominant species observed in Brazil and ...
Borba-Santos LP, Vila T, Rozental S.
europepmc   +2 more sources

Transcriptome-wide expression profiling of Sporothrix schenckii yeast and mycelial forms and the establishment of the Sporothrix Genome DataBase. [PDF]

Microb Genom, 2020
Sporothrix schenckii is a dimorphic fungus existing as mould in the environment and as yeast in the host. The morphological shift between mycelial/yeast phases is crucial for its virulence, but the transcriptional networks implicated in dimorphic ...
Giosa D, Felice MR, Giuffrè L, Aiese Cigliano R, Paytuví-Gallart A, Lo Passo C, Barresi C, D'Alessandro E, Huang H, Criseo G, Mora-Montes HM, de Hoog S, Romeo O.   +12 more
europepmc   +2 more sources

Skin Mast Cells Contribute to Sporothrix schenckii Infection. [PDF]

Front Immunol, 2020
Background: Sporothrix schenckii (S. schenckii), a dimorphic fungus, causes sporotrichosis. Mast cells (MCs) have been described to be involved in skin fungal infections. The role of MCs in cutaneous sporotrichosis remains largely unknown. Objectives: To
Jiao Q, Luo Y, Scheffel J, Geng P, Wang Y, Frischbutter S, Li R, Maurer M, Zhao Z.   +8 more
europepmc   +2 more sources

Sporothrix schenckii and sporotrichosis [PDF]

Anais da Academia Brasileira de Ciências, 2006
For a long time sporotrichosis has been regarded to have a low incidence in Brazil; however, recent studies demonstrate that not only the number of reported cases but also the incidence of more severe or atypical clinical forms of the disease are ...
Leila M. Lopes-Bezerra, Armando Schubach, Rosane O. Costa   +2 more
doaj   +6 more sources

Melanins Protect Sporothrix brasiliensis and Sporothrix schenckii from the Antifungal Effects of Terbinafine. [PDF]

PLoS ONE, 2016
Terbinafine is a recommended therapeutic alternative for patients with sporotrichosis who cannot use itraconazole due to drug interactions or side effects.
Rodrigo Almeida-Paes, Maria Helena Galdino Figueiredo-Carvalho, Fábio Brito-Santos, Fernando Almeida-Silva, Manoel Marques Evangelista Oliveira, Rosely Maria Zancopé-Oliveira   +5 more
doaj   +2 more sources

Screening and transcriptomic analysis of anti-Sporothrix globosa targeting AbaA [PDF]

Frontiers in Microbiology
IntroductionSporotrichosis is a fungal disease caused by a complex of Sporothrix schenckii, leading to chronic infections of the epidermis and subcutaneous tissue in both humans and animals.MethodsThrough virtual screening targeting the key gene abaA to ...
Ying Wang, Xiaoyan Wu, Xiyuan Fan, Chanxu Han, Fangliang Zheng, Zhenying Zhang, Zhenying Zhang   +6 more
doaj   +2 more sources

Cell walls of the dimorphic fungal pathogens Sporothrix schenckii and Sporothrix brasiliensis exhibit bilaminate structures and sloughing of extensive and intact layers.

PLoS Neglected Tropical Diseases, 2018
Sporotrichosis is a subcutaneous mycosis caused by pathogenic species of the Sporothrix genus. A new emerging species, Sporothrix brasiliensis, is related to cat-transmitted sporotrichosis and has severe clinical manifestations.
Leila M Lopes-Bezerra, Louise A Walker, Gustavo Niño-Vega, Héctor M Mora-Montes, Gabriela W P Neves, Hector Villalobos-Duno, Laura Barreto, Karina Garcia, Bernardo Franco, José A Martínez-Álvarez, Carol A Munro, Neil A R Gow   +11 more
doaj   +2 more sources

A novel approach for feline sporotrichosis pathogen detection based on loop-mediated isothermal amplification. [PDF]

Vet Dermatol
Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Amadei S, Campos J, Bertão-Santos A, Frentzel A, Ávila H, Monti FS, Farias MR.   +6 more
europepmc   +2 more sources

Disruption of protein rhamnosylation affects the Sporothrix schenckii-host interaction. [PDF]

Cell Surf, 2021
Tamez-Castrellón AK, van der Beek SL, López-Ramírez LA, Martínez-Duncker I, Lozoya-Pérez NE, van Sorge NM, Mora-Montes HM.   +6 more
europepmc   +2 more sources