Results 41 to 50 of about 6,535 (217)

The Heat Shock Protein 60 and Pap1 Participate in the Sporothrix schenckii-Host Interaction

Journal of Fungi, 2021
Sporothrixschenckii is one of the etiological agents of sporotrichosis, a worldwide-distributed subcutaneous mycosis. Its cell wall contains a glycoconjugate composed of rhamnose, mannose, glucuronic acid, and proteins, named peptidorhamnomannan, which ...
Laura C. García-Carnero, R. Salinas-Marín, Nancy E. Lozoya-Pérez, K. Wrobel, K. Wrobel, I. Martínez-Duncker, Gustavo A. Niño-Vega, H. Mora-Montes   +7 more
semanticscholar   +1 more source

Environmental Isolates of Sporothrix schenckii in China.

Nippon Ishinkin Gakkai Zasshi, 2002
Restriction fragment length polymorphism (RFLP) in mitochondrial DNA (mtDNA) from 25 environmental isolates of Sporothrix schenckii from northeastern China was investigated. Based on the mtDNA-RELP patterns with Hae III, 6 isolates were confirmed to be S. schenckii, while the other 19 isolates were confirmed to be species distinct from S.
Hiroshi Ishizaki, Masako Kawasaki, Takashi Mochizuki, Xue-Zhu Jin, Saburo Kagawa   +4 more
openalex   +5 more sources

The impact of AlphaFold Protein Structure Database on the fields of life sciences

PROTEOMICS, Volume 23, Issue 17, September 2023., 2023
Abstract Arguably, 2020 was the year of high‐accuracy protein structure predictions, with AlphaFold 2.0 achieving previously unseen accuracy in the Critical Assessment of Protein Structure Prediction (CASP). In 2021, DeepMind and EMBL‐EBI developed the AlphaFold Protein Structure Database to make an unprecedented number of reliable protein structure ...
Mihaly Varadi, Sameer Velankar
wiley   +1 more source

Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs

Xenotransplantation, Volume 30, Issue 5, September/October 2023., 2023
Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal, Solenne Costard, Reid Ballard, Stephen Bienhoff, Diana C. Challen, Brandon J. Dominguez, Douglas R. Kern, Dan Miller, Jeske Noordergraaf, Larisa Rudenko, Henk‐Jan Schuurman, Tom Spizzo, Matthew Sturos, Bill Zollers, Jay A. Fishman   +14 more
wiley   +1 more source

Fungal resilience and host–pathogen interactions: Future perspectives and opportunities

Parasite Immunology, Volume 45, Issue 2, February 2023., 2023
Abstract We are constantly exposed to the threat of fungal infection. The outcome—clearance, commensalism or infection—depends largely on the ability of our innate immune defences to clear infecting fungal cells versus the success of the fungus in mounting compensatory adaptive responses.
Alistair J. P. Brown
wiley   +1 more source

Response to Oxidative Stress in <i>Sporothrix schenckii</i>. [PDF]

J Fungi (Basel)
Oxidative stress is key in immune defense against fungal infections, such as those caused by Sporothrix schenckii, the dimorphic fungus responsible for sporotrichosis. Phagocytic cells utilize oxidative stress as a crucial mechanism to control pathogen spread. During S.
Ruiz-Baca E, Adame-Soto PJ, Alba-Fierro CA, Martínez-Rocha AL, Pérez-Torres A, López-Rodríguez A, Romo-Lozano Y.   +6 more
europepmc   +3 more sources

Differential Recognition of Clinically Relevant Sporothrix Species by Human Granulocytes

Journal of Fungi, 2023
Sporotrichosis is a cutaneous mycosis that affects humans and animals and has a worldwide distribution. This infection is mainly caused by Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa.
Ana K. Galván-Hernández, Manuela Gómez-Gaviria, Iván Martínez-Duncker, José A. Martínez-Álvarez, Héctor M. Mora-Montes   +4 more
doaj   +1 more source

Non‐canonical binding of the Chaetomium thermophilum PolD4 N‐terminal PIP motif to PCNA involves Q‐pocket and compact 2‐fork plug interactions but no 310 helix

The FEBS Journal, Volume 290, Issue 1, Page 162-175, January 2023., 2023
The sliding clamp PCNA interacts with numerous protein partners by binding to a conserved PIP (PCNA interacting protein) motif. In this study, we describe the interaction of the N‐terminal PIP motif of the DNA polymerase δ subunit PolD4 from the thermophilic fungus Chaetomium thermophilum with its cognate PCNA, revealing a novel, non‐canonical binding ...
Dongxiao Yang, Magnus S. Alphey, Stuart A. MacNeill   +2 more
wiley   +1 more source

Molecular Epidemiology of Sporothrix schenckii.

Nippon Ishinkin Gakkai Zasshi, 2000
Restriction fragment length polymorphism (RFLP) in mitochondrial DNA (mtDNA) of clinical and environmental isolates of Sporothrix schenckii was investigated. Among mtDNA RFLP patterns with Hae III, of 14 environmental isolates morphologically identified as S. schenckii, only 2 isolates were confirmed as S.
Hiroshi Ishizaki, Masako Kawasaki
openalex   +5 more sources

Sporotrichoid lymphocutaneous pattern in a fish‐merchant under immunosuppressant medications: Clues to differential diagnoses

Clinical Case Reports, Volume 10, Issue 12, December 2022., 2022
Abstract Sporotrichoid‐lymphocutaneous‐pattern is classically seen in sporotrichosis, though also present in other infections like atypical mycobacteriosis and leishmaniasis. Cutaneous atypical mycobacterial infection presents as localized lesions in immunocompetent and is widespread in immunosuppressed patients.
Dhan Keshar Khadka, Ripala Acharya, Sudha Agrawal   +2 more
wiley   +1 more source