Results 131 to 140 of about 1,934,866 (340)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Ethical Dilemmas of Sport Advertising [PDF]

Sport Mont, 2016
The objective of this study represent the sport advertising, while the main goal will be directional to discuss ethical dilemmas of sport advertising. The main tasks of this study is discussing a law regulations and ethics, as well as communication with ...
Duško Bjelica, Jovan Gardašević, Ivan Vasiljević, Stevo Popović   +3 more
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Wolf-hunting and wild sport in lower Brittany [PDF]

, 1875
E. W. L. Davies, Henry Hope Crealocke
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Considerations Regarding the Parents’ Opinions About the Physical Education Lesson in the Secondary Schools of Reșița

Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae
Parents’ attitudes towards physical education lessons can have a significant impact on children and their participation in physical education lessons. If parents show disinterest or have a negative attitude towards the lesson and the physical education ...
Dan-Mihai ROHOZNEANU
doaj   +1 more source

The school sport co-ordinator programme: evaluation of phases 1 and 2 2001–2003 [PDF]

, 2003
This report evaluates the effect of the School Sport Co-ordinator programme (the programme) since its introduction in autumn 2000. The programme is part of the national physical education (PE), School Sport and Club Links strategy led by the Department ...

core  

Assessing the sociology of sport: On critical sport sociology and sport management

International Review for the Sociology of Sport, 2015
On the 50th anniversary of the ISSA and IRSS, Annelies Knoppers, one of the leading scholars in understanding the culture of sport in organizational settings, considers how the critical lens of sociology can enhance and mesh with research on sport management.
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Guideline for Eexercise Therapy of Type 2 Diabetes Mellitus in China (2024 Edition) [PDF]

Zhongguo quanke yixue
National Center of Gerontology, Chinese Diabetes Society, China Sport Science Society
doaj   +1 more source