Results 141 to 150 of about 982,890 (288)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sport-for-development impact study: A research initiative funded by Comic Relief and UK Sport and managed by International Development through Sport

, 2010
First paragraph: This report provides an analysis of data collected as part of a major research project funded by Comic Relief and UK Sport and managed by International Development through Sport (IDS).
Coalter, Fred, Taylor, John
core  

FIM Motorcycling sport-specific extension of the IOC consensus statement: methods for recording and reporting of epidemiological data on injury and illness in sport 2020. [PDF]

BMJ Open Sport Exerc Med
O'Dowd DP, McManus D, Turner M, Brennan HJ, Di Filippo G, D'Artibale E, Filipowski S, King P, Lazzarotti M, Mass S, Petherbridge S, Pluim B, Romer HC, Thumm M, Walker A.   +14 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Relationship between upward social comparison and adolescent depression: moderating roles of football participation. [PDF]

Front Public Health
Zheng Y, Huang H, Li A, Zhong C, Zhang L, Shui Y.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Sport Consumption Through Media [PDF]

The purpose of the present paper is to present a survey designed to describe and to explain the extension and the composition of sport consumption in Portugal. The survey is based on a representative national inquiry. The population is questioned for the
José Viseu
core  

Back Matter

Journal Sport Area, 2019
sport area
doaj  

Female Team-Sport Athletes' Physical Fitness and Jump Performance Kinematics After Plyometric Jump Training: A Systematic Review and Meta-analysis. [PDF]

Sports Med Open
Lane A, Ramirez-Campillo R, Connors P, Bolger R, Moody JA, Thapa RK, Byrne PJ.   +6 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source