Results 91 to 100 of about 97,656 (288)

Sports Climbing Injury Prevention

, 2019
The objective of this article is to bring clear the data about pain, injury and prevention focused in climbing athletes, professionals or non-professionals. Knowing these valuable information’s, some gaps and limitations can possibly be filled with further researches.
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

COMPETITIVES SPORTS PROFILES OF YOGYAKARTA [PDF]

This study aims to determine the pattern of achievement in sports coaching in Yogyakarta, knowing the pattern of performance of the sport organizations, knowing the sport competitive and leading sports characteristics.
Sudarko, Rumpis Agus
core  

High impact activities in parks: best management practice and future research [PDF]

, 2008
Off-road driving, horseriding, rock climbing and similar activities can be lucrative for tour operators and important for local recreational groups, but contentious for management of national parks and protected areas, both because of safety and ...
Buckley, R., Cater, C, Hales, R., Newsome, D., Pickering, C., Smith, A.   +5 more
core   +1 more source

Is consumer behaviour towards footwear predisposing for lower extremity injuries in runners and walkers? : a prospective study [PDF]

, 2019
Background: Runners and walkers often suffer from lower extremity injuries. Little is known about the relationship between their consumer behaviour towards footwear and the development of those injuries.
De Ridder, Roel, Roosen, Philip, Willems, Tine   +2 more
core   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Painfully ignorant? Impact of gender and aim of training on injuries in climbing

BMJ Open Sport & Exercise Medicine
Introduction Climbing has evolved from an obscure outdoor sport to a predominantly indoor sport with the rise of mainstream climbing on artificial walls.
Gudmund Grønhaug, Atle Saeterbakken, Tallie Casucci   +2 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Abnormal electrocardiographic findings in athletes: Correlation with intensity of sport and level of competition. [PDF]

, 2016
INTRODUCTION: Athletes can exhibit abnormal electrocardiogram (ECG) phenotypes that require further evaluation prior to competition. These are apparently more prevalent in high-intensity endurance sports.
Arbab-Zadeh, Brosnan, Corrado, Dores, Drezner, Drezner, Drezner, Friedmann, Gademan, Gati, Koch, Lang, Maron, Papadakis, Pelliccia, Pelliccia, Pelliccia, Pelliccia, Rawlins, Sharma, Sharma, Sheikh, Wilson   +22 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source