Results 91 to 100 of about 475,527 (306)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

SPORT SPECIALIZATION AND COLLEGE SCHOLARSHIP BELIEFS AND FINANCIAL INVESTMENT AMONG HIGH SCHOOL BASEBALL PARENTS

Orthopaedic Journal of Sports Medicine, 2020
BACKGROUND: Youth athletes are increasingly encouraged to specialize in a single sport and participate on club teams year-round to be offered a college scholarship.
Eric G. Post PhD, ATC, Michael D. Rosenthal PT, DSc, ATC, Mitchell J. Rauh PT, PhD, MPH   +2 more
doaj   +1 more source

Profil Tingkat Kemampuan Daya Tahan (Vo2 Max) Atlet Tenis Meja Junior Putra Klub Malay Sport Pekanbaru [PDF]

, 2017
Based on the results of observations made by the researchers of the table tennis junior men athletes Malay Sport Club Pekanbaru, researchers found a problem that athletes often rely on during training, athletes are easily breathless during a physical ...
Dudi, D. (Dudi), Saripin, S. (Saripin), Agust, K. (Kristi)   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Relationship between perceived enjoyment, exercise commitment and behavioral intention among adolescents participating in "School Sport Club". [PDF]

Front Med (Lausanne), 2023
Joung K, Jeon W, Kwon G.
europepmc   +1 more source

Voluntary sport clubs and the social policy agenda [PDF]

, 2016
Local governments, traditionally an important partner of voluntary sport clubs in the Netherlands, are increasingly influencing clubs into involvement in social projects and activities.
Boven, Magda, Slender, Hans, Wiggers, Peter   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Stability of context in sport and exercise across educational transitions in adolescence: hello work, goodbye sport club? [PDF]

BMC Public Health, 2022
Gut V, Schmid J, Imbach L, Conzelmann A.
europepmc   +1 more source

Value of a community football club [PDF]

Research background The Centre for Sport and Social Impact (CSSI) at La Trobe University was commissioned by AFL Victoria to determine the social value of a \u27typical\u27 community football club; specifically its social, health and community impact ...
Centre for Sport and Social Impact (LaTrobe)
core