Results 101 to 110 of about 475,527 (306)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

How the Economic and Financial Situation of the Community Affects Sport Clubs’ Resources: Evidence from Multi-Level Models

open access: yesInternational Journal of Financial Studies, 2015
In many Western countries, local community sport clubs are important providers of leisure, sport, and social programs. These sport clubs are nonprofit organizations, which operate in an increasingly challenging environment.
Pamela Wicker, Christoph Breuer
doaj   +1 more source

Role Ambiguity in Sport Teams [PDF]

open access: yes, 2003
The general purpose of the present study was to examine the nature of role ambiguity in sport teams and to explore the construct validity of the operational definition of role ambiguity developed by Beauchamp, Bray, Eys, and Carron (2002). Role ambiguity
Beauchamp, Mark R.   +3 more
core   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Book Review: Fair Play: The Ethics of Sports

open access: yes, 2011
During the past few years of my collegiate and youth-club coaching career, I have often found myself engrossed with many intellectual tasks in an attempt to improve both myself and my athletes\u27 chances for success.
Joseph, Dane C.
core  

PENGARUH GOLF TRAVEL MOTIVATION TERHADAP SPORT DECISION DI DAGO ENDAH GOLF COURSE : Survey pada Partisipan di Dago Endah Golf Course [PDF]

open access: yes, 2016
Dago Endah Golf Course merupakan salah satu Golf Club tertua di Indonesia, Golf Club yang berada di Kota Bandung ini dibangun pada tahun 1917 menjadikan Dago Endah Golf Course memiliki potensi yang besar dalam wisata olahraga golf.
Misdiantika, Yuni
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Volunteering in sport clubs

open access: yes, 2014
Volunteers are the most important resource for non-profit sport clubs seeking to bolster their viability (e.g. sporting programs). Although many people do voluntary work in sport clubs, stable voluntary engagement can no longer be granted. This difficulty is confirmed by existing research across various European countries.
Nagel, Siegfried, Schlesinger, Torsten
openaire   +2 more sources

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