Results 91 to 100 of about 26,692 (306)

Regulating competitive balance in sport

open access: yes, 2012
Sport is an integral part of popular culture, capturing the hearts and minds of millions of people from every section of society 1. Maintaining competitive balance in sport is essential in preserving its long term survival.
Kashani, O
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Turning a meaningful charity sport event into social change

open access: yes, 2009
Charity sport events continue to increase in popularity and have been shown to provide meaningful experiences for participants. This research evaluates how the meaning derived from a charity sport event translates into social empowerment and social ...
Filo, Kevin
core  

Re-enchanting the Chinese Sport Spectator - A Postmodern perspective on Sport Marketing in China

open access: yes, 2014
The cultural and philosophical heritage of modernism underpinning general marketing management theory imparts profound implications for organisations operating in professional sport.
Cockayne, DC   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Dissecting action sports studies: Past, present, and beyond

open access: yes, 2013
The term “action sports” broadly refers to a wide range of mostly individualized activities such as BMX, kite-surfing, skateboarding, surfing, and snowboarding that differed – at least in their early phases of development – from traditional rule-bound ...
Wheaton, Belinda   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

National knowledge agenda sport and excercise: from the steps to the podium

open access: yes, 2016
A broad agenda with societal urgency — From improving children's learning performances to delaying the onset of Alzheimer's disease. From productive employees to playing football to counteract radicalisation.
Vos, Steven   +9 more
core  

Sport Management Case of a football club

open access: yes, 2023
Sport is an essential element of human life, having countless benefits ranging from improved health, enhanced social interactions, and positive impacts on the economy.
Aloulou, Mohamed Ali
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy