Results 101 to 110 of about 26,692 (306)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Sport Event as a Driver of Mass Sport Development
Вестник Российского экономического университета имени Г. В. ПлехановаRussia has gained large experience in arranging sport events of different scale. Big sport competitions of international level were held, such summer Universiade ‘Kazan-2013’ and winter Universiade in Krasnoyarsk in 2019, a number of world championships ...
E. A. Gureeva
doaj +1 more source
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis explores how coach-athlete relationships are influenced within the organisational culture of a rowing club.
Maitland, Alison
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2011 Aim of paper and research questions: This study seeks to understand Corporate Social Responsibility (CSR) in European sport clubs by analysing and classifying the CSR activities and programs.
Trendafilova, S +3 more
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Economic impact report on the New Zealand sport horse industry
, 2012 The aim of this research paper is to gain an understanding of the size and scope of the sport horse industry in New Zealand. The definition of the sport horse industry is that it comprises of all horses in New Zealand that are not being used for the
Akoorie, Michèle E.M., Matheson, Alex
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Future skills in sport industry
The sport industry is undergoing rapid transformation driven by digitalisation, automation, and the spread of artificial intelligence. These shifts are reshaping workforce demands and raising questions about the adequacy of existing competency models ...
Fošner, Ajda +7 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source