Results 111 to 120 of about 831,003 (288)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Evaluation of the general physical fitness of young sambo wrestlers from “Ardo” and “Pelesa” sports clubs. [PDF]
, 2009 The object of research — physical fitness of young sambo wrestlers. Subjects under study: each 15 sambo wrestlers, aged 9-14 years, from “Pelesa” and “Ardo” sports clubs.
Rindeika, Vitalijus,
core +1 more source
The development of Swiss sports clubs: Membership, volunteering, professionalization
Current Issues in Sport ScienceIntroduction The Swiss Sports Observatory has been conducting the national club survey since 1996. Every six years, the club managers of all sports clubs belonging to an association affiliated to Swiss Olympic are asked to complete a questionnaire ...
Rahel Bürgi +3 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Volunteering In Sports Clubs In Europe [PDF]
, 2017 Voluntary work is still the most important resource that allow clubs to survive and to offer interesting programs to their members. However, volunteering is not only relevant for sport clubs and members, but also for civil society, since inclusion in a ...
Nagel, Siegfried
core
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Systemic Relationship Marketing: Co-creating Sports Brand Equity with Fans and Other Stakeholders [PDF]
Revista de Management Comparat International, 2013 Relationship marketing can be a possibility for sports clubs to improve their brand equity and to deliver added value to their fans. Leading and managing the sports club by a relationship marketing philosophy can help involve the fans into co-creating ...
Vlad ROŞCA
doaj
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source