Results 101 to 110 of about 323,027 (311)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Human resources development of sports club.

open access: yes, 2013
The object: forming human resources in sports club. The objective: to analyze the formation of human resources in sports club \"X\". Work tasks: 1.
Norvaišienė, Lina,
core  

An analysis of County Sports Partnerships in England: the fragility, challenges and complexity of partnership working in sports development

open access: yes, 2011
The management, use and reliance upon multi-agency partnerships in the field of public sector sports development became increasingly important following the election of the ‘New’ Labour government in 1997.
Chris Mackintosh   +2 more
core   +1 more source

Factors influencing sports talent development in Senior High Schools in the Upper East Region of Ghana

open access: yesAfrican Journal of Teacher Education
Despite the increasing interest in examining predictors within sports talent development, there is a dearth of studies in the Ghanaian context. Yet, Senior High Schools (SHSs) in the Upper East Region of Ghana are expected to help talented student ...
Daniel Apaak
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Opportunities of sports systems management and organizational development in Prienai and Jonava regions.

open access: yes, 2012
Opportunities of sports systems management and organizational development in Prienai and Jonava regions Key words: sports system, management and organization development, opportunities, Prienai, Jonava.
Kubilius, Adomas,
core  

Resistance exercise exacerbates muscle atrophy of skeletal muscle-specific Beclin1 conditioned knockout (cKO) mice

open access: yesAdvanced Exercise and Health Science
The autophagy-lysosome pathway is the major route for protein and organelle clearance, and the functional status of autophagy plays an important role in the performance of skeletal muscle.
Zhengzhong Zeng   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Adolescent Involvement in Sports Activities and Internalisation of Moral Values

open access: yes, 2016
Background.  Relatively  little  knowledge  is  available  to  date  about  moral  values  among  adolescents.  As participation  in  sports  activities  may  contribute  to  positive  youth  development,  this  study  aims  to  examine  the relations ...
Kromerova, Enrika, Šukys, Saulius
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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