Results 41 to 50 of about 49,220 (251)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The closer the sportier? Children’s sports activity and their distance to sports facilities [PDF]
European Review of Aging and Physical Activity, 2011 AbstractWe investigate whether the distance between the next sports facilities and children’s homes matter for their sports activities inside and outside of sports clubs. Our analysis is based on a large and informative cross-section of individual data on children and their families, the so-called German Health Interview and Examination Survey for ...
Steinmayr, Andreas +2 more
openaire +4 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of Education, Health and Sport, 2018 This article addresses the issue of the analysis of the development of the communes of the seaside tourist zone of the Polish Baltic Coast. The analysis was carried out for all 37 coastal communes of the coastal tourist zone.
Krzysztof Parzych, Rafał Gotowski
doaj +3 more sources
Regional differences in the economical sustainability of sports halls
Apstract: Applied Studies in Agribusiness and Commerce, 2016 The precondition of a health conscious behaviour in a community is establishing a healthy development of the community, an important part of which is the community’s attitude to sports and health.
Nikolett Kosztin, Ildikó Balatoni
doaj +1 more source
Comparison and Examination of North Carolina State University Sports System and Sports Organizations
Research in Sports Science, 2020 The purpose of this study was to investigate on-site the sports management system and the sports facilities on-site, the functionality of Department of Athletics and the sports organizations of North Carolina (NC) State University (North Carolina, USA ...
Ayşe Türksoy Işım, Burcu Güvendi
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Sports and Sporting Facilities in the Civilization of Pergamum
The Anthropologist, 2015 . Sporting History . Education . Environment . Recreation ABSTRACT The aim of this research is to examine the sports activities in the ancient city of Pergamum using documentary research method. Historical documentation method and the relics such as inscriptions and historical sports areas of the Pergamum and documents found in the city shows it is the
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source