Results 51 to 60 of about 592,383 (293)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Glasgow 2014 Games: Regeneration and Physical Activity Legacy [PDF]

open access: yes, 2014
Both the Scottish Government and Glasgow City Council expressed an intention to use the 2014 Commonwealth Games to inspire more citizens to become physically active.
Clark, Julie, Kearns, Ade
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Sports and Sporting Facilities in the Civilization of Pergamum

open access: yesThe Anthropologist, 2015
. Sporting History . Education . Environment . Recreation ABSTRACT The aim of this research is to examine the sports activities in the ancient city of Pergamum using documentary research method. Historical documentation method and the relics such as inscriptions and historical sports areas of the Pergamum and documents found in the city shows it is the
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Tinjauan Ketersediaan Sarana dan Prasarana Pembelajaran Pendidikan Jasmani dan Kesehatan di SMP Negeri Se-kecamatan Perhentian Raja Kabupaten Kampar [PDF]

open access: yes, 2017
The availability of facilities and infrastructure for physical education learning in SMP Negeri se-Kecamatan Perhentian Raja Kabupaten Kampar still minimal. The research objective to be achieved is to know whether the sports facilities and infrastructure
Candra, A. (Alfi)
core   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Sports, Environment and Climate Change: the Carbon Footprint of Sports Facilities Based on Energy Consumption in Turkey

open access: yesBaltic Journal of Sport and Health Sciences
In this research, it is aimed to make carbon footprint measurements related to energy consumption (electricity, natural gas) in sports facilities belonging to public institutions in Ardahan province in Turkey.
Ahmet Atalay, Sevdagül Demir
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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