Results 71 to 80 of about 49,220 (251)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The relationship between sports facility accessibility and physical activity among Korean adults

open access: yesBMC Public Health, 2016
Background The benefits of physical activity on physical and mental health are well known. The accessibility of sports facilities is reported to have considerable association with the amount of physical activity a person participates in.
Sang Ah Lee   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Spatial Justice and Accessibility: Optimizing Sports Facility Allocation in Tehran

open access: yesLand
The optimal allocation of sport facilities is crucial for urban management, as it enhances public health and improves citizens’ quality of life. This study proposed a novel decision-making approach for optimizing the allocation of sports facilities in a ...
Rohollah Asgari Gandomani   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The impact of individual and environmental interventions on income inequalities in sports participation: explorations with an agent-based model

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2018
Background Income inequalities in sports participation are shaped by a system in which individuals and the environment interact. We developed an agent-based model (ABM) that could represent this system and used it to provide a proof-of-concept of its ...
David J. Blok   +2 more
doaj   +1 more source

Evaluation of Sport Facilities in Sport Cities in Jordan

open access: yesAl-Balqa Journal for Research and Studies, 2020
هدفت هذه الدراسة الى تقويم المنشآت الرياضة في المدن الرياضية في الأردن واستخدم الباحث المنهج الوصفي وقام ببناء أداة الدراسة بعد الرجوع الى المعايير الدولية والدراسات السابقة وتم اجراء معاملي الصدق والثبات لأداة الدراسة. بلغت عينة الدراسة (24) فرداً ممن يعملون في المدن الرياضية ( مدينة الحسين ، مدينة الحسن ، مدينة الأمير محمد، مدينة الأمير حمزة ...
openaire   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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