Results 251 to 260 of about 111,679 (307)

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

open access: yesAdvanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi   +4 more
wiley   +1 more source

Random Time‐Space Coding Metasurfaces for Spatial Control of the Temporal Statistics of Electromagnetic Fields

open access: yesAdvanced Science, EarlyView.
A probabilistic framework based on random time‐space coding metasurfaces enables control of the spatial distribution of electromagnetic fields temporal statistics. By tailoring the marginal and joint distributions of random codes, electromagnetic fields with desired mean and variance patterns are realized, enabling simultaneous transmission and jamming.
Jia Cheng Li   +3 more
wiley   +1 more source

Synergistic muscle coordination of the Paralympic wheelchair tennis champion. [PDF]

open access: yesFront Sports Act Living
Hakariya N   +3 more
europepmc   +1 more source

The current physical activity in persons with disability in Qatar: a cross-sectional study. [PDF]

open access: yesFront Sports Act Living
Pandiyan U   +5 more
europepmc   +1 more source

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