Results 71 to 80 of about 1,041,745 (306)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Management Training in the Sport of Basketball, Handball, Volleyball and Tennis [PDF]
Use management as applied science in sports, creates opportunities for rationalization and systematization of sports activity, based on knowledge and applicability of laws and principles that control the dynamics of phenomena.
Carmen I. RACHITA
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A Model for Eliciting Expert Knowledge into Sports-Specific Knowledge Management Systems [PDF]
Revista de Management Comparat International, 2014 Grounded on literature reviews from knowledge management, information system, marketing, organization science and sports management strategy, the paper proposes a way to build sports-specific knowledge management systems based on expert knowledge to ...
Vlad ROŞCA
doaj
International sport marketing : practical and future research implications
, 2011 Purpose – Sport is a global product and service that many people around the world enjoy playing, watching and participating in. Whilst there has been an abundance of global media attention on sporting events such as the Olympics and World Football ...
Ratten, Hamish, Ratten, Vanessa
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
, 2004 Much has been written in recent years about governance in the areas of political science, public policy, local government and international relations. However, little research effort has been devoted to examining the term in relation to the organisation,
Hindley, D
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Sports Business and Multisided Markets: Towards a New Analytical Framework? (Long Version) [PDF]
Despite still being younger than a decade, the theory of multisided markets has offered numerous valuable insights for the analysis of industries in which a supplier serves two distinct customer groups that are indirectly interrelated through ...
Janina Satzer, Oliver Budzinski
core +1 more source