Results 91 to 100 of about 927,389 (334)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Changing Minds: Bounded Rationality and Heuristic Processes in Exercise-Related Judgments and Choices [PDF]
, 2016 Experiment 2 was supported by an Outstanding Graduate Student Research Project 20 Award by the Midwest chapter of the American College of Sports ...
Ekkekakis, P, Kavetsos, G, Zenko, Z
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Medical English in Italian University Courses in Sports Sciences: Some Issues in Focus [PDF]
, 2014 Over the last few decades, the increasingly rapid progress of medical science and technology, together with the growing importance of English as the language of international communication, has made the study of medical English a crucial segment in the ...
CAPPUZZO, Barbara
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Factors Influencing Patient Selection of an Orthopaedic Sports Medicine Physician [PDF]
, 2017 Blaine T. Manning +8 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Femoroacetabular Impingement (FAI) Syndrome : the medical imaging perspective [PDF]
, 2014 Introduction: Sports persons, physicians, orthopods and radiologists have become increasingly aware of the extra stress that is imposed on the hip joints with excessive activity particularly when superadded weight bearing and asymmetrical variations from
Zammit, Anthony
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Fitness for fans: professional football and public health [PDF]
, 2017 The benefits of an active life – such as improved mental health and lowered risk of type 2 diabetes, heart disease and some cancers – are well known amongst sports and exercise medicine professionals.
Bunn, Christopher
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