Results 51 to 60 of about 23,589 (303)

miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis

Molecular Therapy: Nucleic Acids, 2018
Fibrosis is common after skeletal muscle injury, undermining tissue regeneration and function. The mechanism underlying skeletal muscle fibrosis remains unveiled.
Yaying Sun, Hui Wang, Yan Li, Shaohua Liu, Jiwu Chen, Hao Ying   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of nutritional knowledge level, daily physical activity and attitudes of sport students of Trakya University Kirkpinar School of Physical Education and Sports and Faculty of Health sciences

, 2021
Yüksek LisansBu araştırma, Trakya Üniversitesi Kırkpınar Beden Eğitimi Yüksekokulu ve Sağlık Bilimleri Fakültesi'nde öğrenim gören gönüllü 400 öğrencinin katılımıyla yürütülmüştür.
Arapoğlu, Çiğdem
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Comparative analysis of fatty acid profiles across omnivorous, flexitarians, vegetarians, and vegans: insights from the NuEva study

Lipids in Health and Disease
Background Different dietary choices can influence blood fatty acid profiles, which are crucial for maintaining physiological health and reducing disease risk.
Lea Klein, Claudia Lenz, Karsten Krüger, Stefan Lorkowski, Kristin Kipp, Christine Dawczynski   +5 more
doaj   +1 more source

Anthropometric Characteristics and Body Composition Changes in a Five-Time Olympic Champion in Greco-Roman Wrestling: A Longitudinal Case Study Towards the Paris 2024 Olympic Games

Journal of Functional Morphology and Kinesiology
Purpose: This case study examines the anthropometric characteristics and body composition changes of a 41-year-old Cuban Greco-Roman 130 kg wrestler, a five-time Olympic gold medalist (2008–2024).
Wiliam Carvajal-Veitía, Carlos Abraham Herrera-Amante, Rodrigo Yáñez-Sepúlveda, Vladimir Gainza-Pérez, Yanell Deturnell-Campos, Carlos Cristi-Montero, Guillermo Cortés-Roco, César Octavio Ramos-García   +7 more
doaj   +1 more source

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

Redox Biology, 2022
Aging is considered a state of low grade inflammation, occurring in the absence of any overt infection often referred to as ‘inflammaging'. Maintaining intestinal homeostasis may be a target to extend a healthier status in older adults.
Annette Brandt, Anja Baumann, Angélica Hernández-Arriaga, Finn Jung, Anika Nier, Raphaela Staltner, Dragana Rajcic, Christian Schmeer, Otto W. Witte, Barbara Wessner, Bernhard Franzke, Karl-Heinz Wagner, Amélia Camarinha-Silva, Ina Bergheim   +13 more
doaj   +1 more source

Investigation of the Relationship between the Social Appearence Anxiety and Nutritional Habits of the Students at the Faculty of Sports Sciences

, 2020
The aim of this study is to investigate the relationship between social appearance anxiety and nutritional habits of the students at the faculty of sports ...
TÜRKAY, İbrahim Kubilay, Arslan, Tuba Akgul   +1 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Relating Anthropometric Profile to Countermovement Jump Performance and External Match Load in Mexican National Team Soccer Players: An Exploratory Study

Sports
Background/Objectives: The role of body composition in sports performance has been widely studied, particularly in soccer. Understanding how anthropometric characteristics impact movement efficiency and neuromuscular performance is crucial for optimizing
Israel Rios-Limas, Carlos Abraham Herrera-Amante, Wiliam Carvajal-Veitía, Rodrigo Yáñez-Sepúlveda, César Iván Ayala-Guzmán, Luis Ortiz-Hernández, Andrés López-Sagarra, Pol Lorente-Solá, José Francisco López-Gil   +8 more
doaj   +1 more source