Results 71 to 80 of about 11,687,561 (330)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Comparative analysis of fatty acid profiles across omnivorous, flexitarians, vegetarians, and vegans: insights from the NuEva study

Lipids in Health and Disease
Background Different dietary choices can influence blood fatty acid profiles, which are crucial for maintaining physiological health and reducing disease risk.
Lea Klein, Claudia Lenz, Karsten Krüger, Stefan Lorkowski, Kristin Kipp, Christine Dawczynski   +5 more
doaj   +1 more source

Bilateral strength asymmetry in knee extension: a reliability and consistency analysis for scientific and practical applications

Frontiers in Sports and Active Living
BackgroundMuscular strength imbalances are associated with musculoskeletal injuries and performance deficits. This study aimed to assess the reliability and consistency of bilateral strength asymmetry (BSA) in quadriceps muscles as determined by ...
Manfred Zöger, Manfred Zöger, Manfred Zöger, Alfred Nimmerichter, Alfred Nimmerichter, Alfred Nimmerichter, Arnold Baca, Arnold Baca, Klaus Wirth   +8 more
doaj   +1 more source

miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis

Molecular Therapy: Nucleic Acids, 2018
Fibrosis is common after skeletal muscle injury, undermining tissue regeneration and function. The mechanism underlying skeletal muscle fibrosis remains unveiled.
Yaying Sun, Hui Wang, Yan Li, Shaohua Liu, Jiwu Chen, Hao Ying   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Associations between disordered eating, body dissatisfaction, and low energy availability in women collegiate athletes

Journal of the International Society of Sports Nutrition
Background Collegiate women athletes face unique challenges regarding nutrition, body image, and athletic performance, which increase their risk for low energy availability (LEA).
Christy V. Le, Andrew R. Jagim, Margaret T. Jones, Jennifer B. Fields   +3 more
doaj   +1 more source

Exercise, Sports & Cardiovascular Health: Relevant Questions and Answers

International Journal of Cardiovascular Sciences, 2019
Mailing Address: Claudio Gil Exercise Medicine Clinic CLINIMEX Rua Siqueira Campos, 93-101. Postal Code: 22031-072, Rio de Janeiro, RJBrazil. E-mail: cgaraujo@iis.com.br Exercise, Sports & Cardiovascular Health: Relevant Questions and Answers Claudio Gil
CLAUDIO GIL ARAUJO, B. Franklin, J. Laukkanen, J. Myers, J. Niebauer, J. Scharhag, Phillip J. Millar   +6 more
semanticscholar   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Periodized carbohydrate intake influences metabolic flexibility and indices of running economy during endurance training in recreationally active males

Frontiers in Nutrition
PurposeLimited research has explored the long-term impact of diet periodization on metabolism, performance, and body composition. This eight-week study examined the effects of long-term periodized carbohydrate (CHO) intake on performance, substrate ...
Anna Maria Kripp, Anna Maria Kripp, Anna Maria Kripp, Andreas Feichter, Daniel König, Daniel König, Daniel König   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source