Results 71 to 80 of about 825,896 (353)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Configuration path analysis of Chinese government sports expenditure promoting national participation in physical activity

open access: yesFrontiers in Public Health
Focusing on the theoretical logic of Chinese government sports expenditure promoting public participation in sports, this study takes 31 provinces (cities, autonomous regions) in China as research objects and uses fsQCA to explore the configurational ...
Wenxin Zhu, Zhihao Du
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The impact of sports participation, spontaneous sports, and motivational factors on the physical fitness of university students in Fuzhou

open access: yesBMC Public Health
Background This study seeks to propose and empirically test a conceptual model that elucidates the complex interrelationships among sports participation, spontaneous sports, sports motivation, lifelong sports, and physical fitness among university ...
Xiangfei Zhu   +3 more
doaj   +1 more source

The relationship between extracurricular sports participation and subjective well-being in junior high school students: a moderated mediation model

open access: yesFrontiers in Public Health
ObjectiveTo investigate the direct effect of extracurricular sports participation on subjective well-being among junior high school students, and the mediating role of emotion regulation and moderating role of physical education (PE) class participation ...
Feifei Li   +5 more
doaj   +1 more source

Examining the relationship between sports participation and youth developmental outcomes for socially vulnerable youth

open access: yesBMC Public Health, 2018
Background Research has shown that sports participation is positively related to youth developmental outcomes, but it is still unknown if sports participation relates to these outcomes among socially vulnerable youth.
Sabina Super   +3 more
doaj   +1 more source

Homophobia, Heterosexism, and Ambivalence in the Premier Issue of \u3cem\u3eSports Illustrated Woman/Sport\u3c/em\u3e [PDF]

open access: yes, 2010
The arrival of a magazine dedicated solely to the world of women\u27s sports was an exciting prospect for fans and proponents of women\u27s sports. But the first issue of Sports Illustrated Women/Sport disappointed many who considered it did not put ...
Weidman, Lisa M.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Impact of Motivational Factors on Daily Fantasy Sports Participation [PDF]

open access: yes, 2016
Since the passing of the Unlawful Internet Gambling Act (UIGEA) in 2006, the fantasy sports world has had a tumultuous decade. Shortly after the passing of UIGEA, daily fantasy sports became marketable, and saw several years of tremendous growth. However,
O\u27Hern, Matthew, Phelan, Brendan
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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