Results 91 to 100 of about 246,734 (314)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Introduction: Several physiological tests have been developed to predict cycling performance. However, the high costs and expertise needs to perform these tests detracts coaches and athletes from using them habitually. The aim of this study is to provide
Ricardo Morán-Navarro +4 more
doaj
Mini-Open Rotator Cuff Repair Technique
Background: Before the rise of arthroscopic rotator cuff repair (RCR), mini-open RCR was the preferred method of repairing a torn rotator cuff. However, in the recent fluid shortage that limited the viability of performing arthroscopic procedures, we ...
Nicholas Bertha MD +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The aim of this study was to determine the acute effects of wearable resistance forearm (WRf) loading versus shank (WRs) loading on change of direction (COD) performance in netball athletes.
Chloe Ryan +3 more
doaj +1 more source
Estimation of optimal Lithuanian sports federation performance evaluation criteria‘s.
Estimation of optimal Lithuanian sports federation performance evaluation criteria ...
Vyštartaitė, Gabrielė,
core
Olympic sports science – Bibliometric analysis of all summer and winter Olympic sports research
International audienceIntroduction: The body of scientific literature on sports and exercise continues to expand. The summer and winter Olympic games will be held over a 7-month period in 2021–2022.Objectives: We took this rare opportunity to quantify ...
Brocherie, Franck +5 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

