Results 241 to 250 of about 401,963 (312)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Aortic Root Enlargement in a Young Athlete. [PDF]

JACC Case Rep
Jiang NM, O'Connor C, Engel DJ.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Aortic Root Dilation in a Masters Dressage Athlete With Familial TAAD. [PDF]

JACC Case Rep
El Hri H, Daems JJN, van Diepen MA, Verwijs SM, Groenink M, Moen MM, Bijsterveld NR, Jørstad HT.   +7 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Williamson Central School District and Williamson Faculty Association (2007) [PDF]

, 2007

core   +1 more source

"We ensure that children and young people have a place to be and something meaningful to do". Sustainable development in the Norwegian riding schools. [PDF]

Front Sports Act Living
Radmann A, Kronborg M, Sätre A, Andersson P, Torell Palmquist G, Hedenborg S.   +5 more
europepmc   +1 more source

America’s Bad Bet: How The Unlawful Internet Gambling Enforcement Act Of 2006 Will Hurt The House [PDF]

, 2007
Shaker, PeterPaul, J.D.
core   +1 more source

Influence of suit size and air permeability on performance in ski jumping. Part I: wind tunnel measurements. [PDF]

Front Sports Act Living
Virmavirta M, Müller S, Kürschner M, Bessone V, Krężałek P, Elfmark O.   +5 more
europepmc   +1 more source

COTPA Section 4 Compliance in Udupi City Municipal Corporation: An Exploratory Survey From Coastal Karnataka. [PDF]

Int J Dent
Singla N, Tauro VE, Dutta K, Pradhan A, Singla R, Pradeep J, Sarmah B, Singhal DK.   +7 more
europepmc   +1 more source