Results 71 to 80 of about 723,629 (313)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 1980 SPoT Coffee has been proudly operating in New York State since 1996. The company designs, builds, operates and franchises community-oriented cafés that provide customers with world class service, signature dishes and gourmet coffee roasted in-house. SPoT’
Spot Coffee
core
Relación entre los mercados spot y de futuros en un contexto oligopolístico [PDF]
, 1999 Existe una reciente literatura sobre la relación entre los mercados spot y de futuros. En ella se encuentra un efecto pro-competitivo de estos últimos.
Herguera, Iñigo, Ferreira, José Luis
core
Retoryczno-obyczajowe tło kampanii medialnej OLX
Res Rhetorica, 2019 A gdyby tak potraktować komunikację nakłaniającą niestandardowo? Gdyby, zamiast reklamować swoje usługi, pokazać manifest nietolerancji dla braku kultury?
Anna M. Kiełbiewska
doaj +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frank and Mary One Spot interview
, 1983 28 p. transcript of an interview with Frank and Mary One Spot conducted by Tony Snowsill on July 5, 1983. Tape number IH-156, transcript disc 7.Frank and Mary One Spot give a general account of the movement of the Sarcee Indians ...
One Spot, Frank +2 more
core
Personajes y discurso emocional en las campañas de la DGT. Análisis de los spots de 2007-2011
Historia y Comunicación Social, 2014 En este trabajo se muestra la importancia de la apelación emocional como medio persuasivo en los spots publicitarios de la Dirección General de Tráfico desde 2007 hasta 2011, identificando las emociones más representadas en el discurso audiovisual, el ...
Rosario Segura García
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
White spot syndrome virus envelope protein VP28 is involved in the systemic infection of shrimp [PDF]
, 2001 White spot syndrome virus (WSSV) is a large DNA virus infecting shrimp and other crustaceans. The virus particles contain at least five major virion proteins, of which three (VP26, VP24, and VP15) are present in the rod-shaped nucleocapsid and two (VP28 ...
van Hulten, Mariëlle C W +8 more
core +1 more source