Results 131 to 140 of about 567,593 (331)

Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino   +3 more
wiley   +1 more source

Atypical fulminant Rickettsia rickettsii infection (Brazilian spotted fever) presenting as septic shock and Adult Respiratory Distress Syndrome

open access: yesBrazilian Journal of Infectious Diseases
Brazilian spotted fever, caused by Rickettsia rickettsii, has been increasingly reported in Brazil especially in the southeastern states. The severe and fulminant forms of the disease are not unusual but most of the reported fatal cases have shown some ...
Paulo Sérgio Gonçalves da Costa   +3 more
doaj   +1 more source

Spotted fever group rickettsiae in ticks of migratory birds in Romania

open access: yesParasites & Vectors, 2016
Birds are important hosts and dispersers of parasitic arthropods and vector-borne zoonotic pathogens. Particularly migratory species may carry these parasites over long distances in short time periods. Migratory hotspots present ideal conditions to get a
Ioan-Daniel Mărcuţan   +6 more
semanticscholar   +1 more source

Epidemiological characteristics of Brazilian spotted fever in Minas Gerais State, Brazil, 2000-2008

open access: yesCadernos de Saúde Pública, 2011
Brazilian spotted fever is the most common rickettsiosis in Brazil, most prevalent in the States of São Paulo and Minas Gerais. The aim of this study was to describe the epidemiological characteristics of Brazilian spotted fever in Minas Gerais from 2000
Frederico Figueiredo Amâncio   +7 more
doaj   +1 more source

Immunology of human rickettsial diseases. [PDF]

open access: yes, 2008
Among human rickettsial diseases caused by micro-organisms of the genus Rickettsia (Order Rickettsiales; Family Rickettsiaceae), transmitted to human hosts through arthropod vectors, Mediterranean Spotted Fever, or Boutonneuse Fever, and Rocky Mountain ...
ARCOLEO F   +5 more
core  

Auricular Perichondritis in the Cartilage Piercing Era

open access: yesThe Laryngoscope, EarlyView.
The demographics, clinical presentation, treatment, and complications of piercing‐induced auricular perichondritis (P‐IAP) and piercing‐free auricular perichondritis (P‐FAP) were studied. P‐IAP has different demographics, comorbidities, disease course, and microbiology compared to P‐FAP.
Omer J. Ungar   +7 more
wiley   +1 more source

Tick borne illness in Missouri [PDF]

open access: yes, 2014
Missouri is a hotbed for tick-borne illness given its abundance of rural geography and wildlife, especially deer. The two most frequently encountered ticks in Missouri are the lone star tick, Amblyomma americanum and the American dog tick, Dermacentor ...
Roland, William E.
core  

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Spectroscopic, X‐Ray Crystallographic, and Hirshfeld Surface Analyses for the Investigation of Intermolecular Interactions in Carboxamide Hydrazone Hybrids

open access: yesChemistryOpen, EarlyView.
Two novel carboxamide hydrazone hybrids are synthesized and characterized. Structural, spectroscopic, and computational analyses reveal dominant hydrogen bonding, π–π stacking, and reactive sites. Compound 2b exhibits potent antibacterial activity against Staphylococcus aureus, highlighting its potential as a cost‐effective therapeutic agent.
Nabila A. Kheder   +6 more
wiley   +1 more source

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