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TRIM56-mediated production of type I interferon inhibits intracellular replication of Rickettsia rickettsii [PDF]

open access: yesMicrobiology Spectrum
Rickettsia rickettsii (R. rickettsii), the causative agent of Rocky Mountain spotted fever (RMSF), is the most pathogenic member among Rickettsia spp.
Ruxi Cheng   +10 more
doaj   +3 more sources

Identification of Novel Surface-Exposed Proteins of Rickettsia rickettsii by Affinity Purification and Proteomics [PDF]

open access: yesPLoS ONE, 2014
Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is the most pathogenic member among Rickettsia spp. Surface-exposed proteins (SEPs) of R. rickettsii may play important roles in its pathogenesis or immunity.
Wenping Gong, Xiaolu Xiong, Yong Qi
exaly   +3 more sources

Genome Sequence of the Endosymbiont Rickettsia peacockii and Comparison with Virulent Rickettsia rickettsii: Identification of Virulence Factors [PDF]

open access: yesPLoS ONE, 2009
Rickettsia peacockii, also known as the East Side Agent, is a non-pathogenic obligate intracellular bacterium found as an endosymbiont in Dermacentor andersoni ticks in the western USA and Canada.
Roderick F Felsheim
exaly   +3 more sources

Experimental infection of wild boars (Sus scrofa) with Rickettsia rickettsii and evaluation of the transmission potential to Amblyomma sculptum ticks [PDF]

open access: yesParasites & Vectors
Background Brazilian spotted fever is a tick-borne disease caused by the bacterium Rickettsia rickettsii, whose main vector in Brazil is the tick Amblyomma sculptum.
Lucianne Cardoso Neves   +14 more
doaj   +2 more sources

Simultaneous serological assessment of four zoonotic rickettsiae among dogs near the United States-Mexico border. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Obligately intracellular rickettsiae cause a broad spectrum of disease in humans and animals, ranging from mild illness to life-threatening infections. Multiple species co-circulate along the southern United States of America-northern Mexico border, yet ...
Francesca Rubino   +8 more
doaj   +2 more sources

Autophagy facilitates intracellular survival of pathogenic rickettsiae in macrophages via evasion of autophagosomal maturation and reduction of microbicidal pro-inflammatory IL-1 cytokine responses

open access: yesMicrobiology Spectrum, 2023
The genus Rickettsia is comprised of obligate intracellular bacterial parasites of a wide range of arthropod and vertebrate hosts. Some Rickettsia species (spp.) are responsible for serious human diseases globally.
Oliver H. Voss   +6 more
doaj   +1 more source

Significant Growth by Rickettsia Species within Human Macrophage-Like Cells Is a Phenotype Correlated with the Ability to Cause Disease in Mammals

open access: yesPathogens, 2021
Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent of ...
M. Nathan Kristof   +5 more
doaj   +1 more source

Long term neurologic sequelae in a Mexican rocky mountain spotted fever case

open access: yesBrazilian Journal of Infectious Diseases, 2019
During the second half of the twentieth century, neurologic sequelae associated with central nervous system impairment caused by Rickettsia rickettsii were studied widely and exclusively in the United States.
Karla Rossanet Dzul-Rosado   +4 more
doaj   +1 more source

Comparative growth of spotted fever group Rickettsia spp. strains in Vero cells

open access: yesMemorias do Instituto Oswaldo Cruz, 2016
In Brazil, the spotted fever group (SFG) Rickettsia rickettsii and Rickettsia parkeri related species are the etiological agents of spotted fever rickettsiosis. However, the SFG, Rickettsia rhipicephali, that infects humans, has never been reported.
Arannadia Barbosa Silva   +8 more
doaj   +1 more source

Serosurvey of antibodies against spotted fever group Rickettsia spp. in horse farms in Northern Paraná, Brazil Soroprevalência de anticorpos contra Rickettsia spp. do grupo febre maculosa em equinos de haras no Norte do Paraná, Brasil

open access: yesRevista Brasileira de Parasitologia Veterinária, 2010
Brazilian spotted fever (BSF) is an emerging disease most likely caused by Rickettsia rickettsii. The objective of the present study was to estimate the seroprevalence of BSF rickettsia infections in equines from six horse farms located in Londrina ...
Katia Tamekuni   +8 more
doaj   +1 more source

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