Identification of novel surface-exposed proteins of Rickettsia rickettsii by affinity purification and proteomics. [PDF]
PLoS ONE, 2014 Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is the most pathogenic member among Rickettsia spp. Surface-exposed proteins (SEPs) of R. rickettsii may play important roles in its pathogenesis or immunity.
Wenping Gong +5 more
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Fatal Human Infection with Rickettsia rickettsii, Yucatán, Mexico
Emerging Infectious Diseases, 2006 The first fatal Rickettsia rickettsii infection was diagnosed in the southwest of Mexico. The patient had fever, erythematous rash, abdominal pain, and severe central nervous system involvement with convulsive crisis. The diagnosis of R.
Jorge E. Zavala-Castro +8 more
doaj +3 more sources
Genome sequence of the endosymbiont Rickettsia peacockii and comparison with virulent Rickettsia rickettsii: identification of virulence factors. [PDF]
PLoS ONE, 2009 Rickettsia peacockii, also known as the East Side Agent, is a non-pathogenic obligate intracellular bacterium found as an endosymbiont in Dermacentor andersoni ticks in the western USA and Canada.
Roderick F Felsheim +2 more
doaj +3 more sources
Nitric Oxide Inhibition of Rickettsia rickettsii. [PDF]
Infect Immun, 2021 Rickettsia rickettsii , the causative agent of Rocky Mountain spotted fever, is an enzootic, obligate, intracellular bacterial pathogen. Nitric oxide (NO) synthesized by the inducible NO synthase (iNOS) is a potent antimicrobial component of innate immunity and has been implicated in the control of virulent ...
Fitzsimmons LF, Clark TR, Hackstadt T.
europepmc +3 more sources
Selective fragmentation of the trans-Golgi apparatus by Rickettsia rickettsii. [PDF]
PLoS Pathog, 2020 Aistleitner K +3 more
europepmc +2 more sources
Absorption of Rickettsia rickettsii antibodies by Rickettsia rickettsii antigens in four diagnostic tests [PDF]
Journal of Clinical Microbiology, 1983 Immunoabsorption profiles were determined for Rickettsia rickettsii antigens used in four confirmatory tests for detection of antibodies to Rocky Mountain spotted fever. A human serum reactive in the four tests was absorbed with each test antigen and then reexamined by all four tests.
K E, Hechemy +4 more
openaire +2 more sources
Pathogens, 2021 Rickettsia are significant sources of tick-borne diseases in humans worldwide. In North America, two species in the spotted fever group of Rickettsia have been conclusively associated with disease of humans: Rickettsia rickettsii, the causative agent of ...
M. Nathan Kristof +5 more
doaj +1 more source
Laboratory Maintenance of Rickettsia rickettsii [PDF]
Current Protocols in Microbiology, 2008 AbstractThis unit includes protocols for the laboratory maintenance of the obligate intracellular bacterium Rickettsia rickettsii, including propagation in mammalian cell cultures, as well as isolation, counting, and storage procedures. Regulations for working with R. rickettsii in biosafety level 3 containment are also discussed. Curr.
Nicole C, Ammerman +2 more
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Genomic Comparison of Virulent Rickettsia rickettsii Sheila Smith and Avirulent Rickettsia rickettsii Iowa [PDF]
Infection and Immunity, 2008 ABSTRACT Rickettsia rickettsii is an obligate intracellular pathogen that is the causative agent of Rocky Mountain spotted fever. To identify genes involved in the virulence of R. rickettsii , the genome of an avirulent strain, R.
Damon W, Ellison +5 more
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Hosts mobility and spatial spread of Rickettsia rickettsii. [PDF]
PLoS Comput Biol, 2018 There are a huge number of pathogens with multi-component transmission cycles, involving amplifier hosts, vectors or complex pathogen life cycles. These complex systems present challenges in terms of modeling and policy development. A lethal tick-borne infectious disease, the Brazilian Spotted Fever (BSF), is a relevant example of that.
Polo G +4 more
europepmc +7 more sources