Results 71 to 80 of about 565,621 (377)
Case Report: Concurrent Sympatric Scrub Typhus and Japanese Spotted Fever in Japan.
American Journal of Tropical Medicine and Hygiene, 2018 Scrub typhus and Japanese spotted fever-both rickettsial diseases-are endemic and notifiable in Japan and may cause a fatal outcome without prompt treatment.
E. Sando +9 more
semanticscholar +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Rickettsia parkeri in Amblyomma maculatum Ticks, North Carolina, USA, 2009–2010
Emerging Infectious Diseases, 2011 We detected Rickettsia parkeri in 20%−33% of Amblyomma maculatum ticks sampled in North Carolina. Results highlight the high frequencies of R. parkeri–infected ticks in the state with the highest annual incidence of Rocky Mountain spotted fever ...
Andrea S. Varela-Stokes +3 more
doaj +1 more source
Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports [PDF]
, 2015 We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae.
BONURA, Celestino +7 more
core
Advanced Science, EarlyView.Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu +16 more
wiley +1 more source
Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing
Emerging Infectious Diseases, 2017 After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R.
Rikki M.A. Graham +3 more
doaj +1 more source
MMWR Recommendations and Reports, 2016 Tickborne rickettsial diseases continue to cause severe illness and death in otherwise healthy adults and children, despite the availability of low-cost, effective antibacterial therapy.
Holly M. Biggs +15 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen +12 more
wiley +1 more source
Spotted Fever Group Rickettsiae in Inner Mongolia, China, 2015–2016
Emerging Infectious Diseases, 2018 We found Rickettsia raoultii infection in 6/261 brucellosis-negative patients with fever of unknown origin in brucellosis-endemic Inner Mongolia, China. We further identified Hyalomma asiaticum ticks associated with R. raoultii, H.
Gaowa +15 more
semanticscholar +1 more source
Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]
, 2018 Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J +6 more
core +2 more sources