Results 141 to 150 of about 9,767,869 (284)

Challenges in Gene‐Directed Therapies for Rare Neurodevelopmental Disorders Using HNRNPU as an Exemplar

Clinical Genetics, EarlyView.
Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun, Susan F. Rogers, Doaa M. Taha, Meena Balasubramanian   +3 more
wiley   +1 more source

“The Smell Makes Us Hungry”: When Food Is Not Medicine in Highland Madagascar

Culture, Agriculture, Food and Environment, EarlyView.
ABSTRACT In the wake of major disruptions to global supply chains during the Covid‐19 pandemic, the island nation of Madagascar pursued initiatives for auto‐suffisance, self‐sufficiency, in food supplies and medical treatments. Farming communities in the central highlands experienced an injunction to expand cultivation of both subsistence crops and ...
Gabrielle Robbins
wiley   +1 more source

Fibrillar‐Type Dermatitis Herpetiformis: An Underrecognized Variant That Is Rarely Associated With Celiac Disease and Lacking Epidermal Transglutaminase Deposition: A Report of Two Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman, Elodie Mendels, Sven van der Woude, Sharon Veenbergen, Gilles F. H. Diercks, Martijn B. van Doorn   +5 more
wiley   +1 more source

Rickettsia africae and other unclassified Rickettsia species of the spotted fever group in ticks of the Western Ghats, India. [PDF]

Exp Appl Acarol, 2023
Babu NN, Jayaram A, Auti AM, Bhandari Y, Shetty U, Arunkumar G.   +5 more
europepmc   +1 more source

Out of the Ordinary, but Not Out of the Question: Atypia in Pancreatic Lesions Is Not Always Carcinoma

Cytopathology, EarlyView.
An incidental pancreatic lesion in a 69‐year‐old woman was sampled by EUS‐guided fine‐needle biopsy. Integrated cytopathological and histopathological evaluation with immunochemical staining supported organ‐preserving surgery. ABSTRACT Pancreatic perivascular epithelioid cell tumours (PEComas) are exceptionally rare mesenchymal neoplasms.
Maja Kebe Radulovic, Branislava Rankovic, Ajda Toni, Margareta Zlajpah, Darko Siuka   +4 more
wiley   +1 more source

The Datafication of Community Health Work: Discipline, Visibility and the State

Development and Change, EarlyView.
ABSTRACT There has been a concerted drive to expand the scope of ‘data for development’, with a focus on novel technologies. This article highlights a relatively overlooked category of worker in the large‐scale production of such data: volunteers. The authors examine community health as the last frontier of the ‘datafication’ of health, but which forms
Kathy Dodworth, Jean‐Benoît Falisse
wiley   +1 more source

Spotted fever group Rickettsia infection kinetics and cutaneous host response during single tick feeding events. [PDF]

PLoS Pathog
Suwanbongkot C, Langohr IM, Brewer KZ, Barrington RA, Macaluso KR.   +4 more
europepmc   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Prevalence and Species Diversity of Spotted Fever Group Rickettsiae in Ixodid Ticks Collected in Northwest Russia. [PDF]

Trop Med Infect Dis
Karmokov I, Freylikhman O, Baimova R, Grechishkina D, Lunina G, Lyzenko I, Riabiko E, Arbuzova T, Bachevskaia A, Ramsay E, Khalilov E, Kukleva K, Bespyatova L, Bugmyrin S, Petrov M, Neverova O, Titarchuk K, Agasoi V, Kalinin N, Vorobyeva O, Mikheenko O, Iakimenko T, Druzhinina I, Matina O, Monastyrskaya-Nuzhina D, Smirnova A, Tokarevich N.   +26 more
europepmc   +1 more source

Diversity and Phylogeny of Cattle Ixodid Ticks and Associated Spotted Fever Group Rickettsia spp. in Tunisia. [PDF]

Pathogens, 2023
Kratou M, Belkahia H, Selmi R, Andolsi R, Dhibi M, Mhadhbi M, Messadi L, Ben Said M.   +7 more
europepmc   +1 more source