Results 111 to 120 of about 253,751 (300)
Advanced Science, EarlyView.By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source
DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout
Advanced Science, EarlyView.A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li +12 more
wiley +1 more source
A Review of Crohn’s Disease [PDF]
European Medical Journal Gastroenterology, 2013 Crohn’s disease is a chronic relapsing inflammatory bowel disease that may affect any part of the gastrointestinal tract. The ileum, colon, and perineum are most commonly affected.
Philip Hendy, Ailsa Hart
doaj
A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy
Advanced Science, EarlyView.ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun +12 more
wiley +1 more source
Integrate range shifter in immobilization for proton therapy: 3D printed materials characterization [PDF]
, 2016 3D printing is investigated for application in patient immobilization during proton therapy (PT). It potentially enables a merge of immobilization, range shifting and other functionality into one patient-specific structure.
D'Hollander, Antoine +9 more
core +1 more source
Advanced Science, EarlyView.This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang +14 more
wiley +1 more source
International Journal of NanomedicineJingyao Zhang,1 Beibei Liu,1 Hongying Chen,1 Lingshu Zhang,2 Xia Jiang3 1Core Facilities of West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 2Department of Rheumatology and Immunology, West China Hospital ...
Zhang J, Liu B, Chen H, Zhang L, Jiang X
doaj
Superlattice Architectures for Advancing Photothermal Catalysis: Mechanisms and Applications
Advanced Science, EarlyView.This paper provides a timely overview of superlattice architectures in photothermal catalysis, with a systematic review on mechanisms at both atomic and macroscopic scales in different processes, challenges, and future opportunities. ABSTRACT Photothermal catalysis has emerged as a powerful strategy to complement photocatalysis by harnessing full ...
Yuzhao Wu +5 more
wiley +1 more source
Pengendalian pilihan raya dalam perlembagaan: perlu penilaian semula? [PDF]
, 2014 Perlembagaan menyediakan asas perundangan berkaitan dengan pengendalian pilihan raya di Malaysia. Penubuhan Suruhanjaya Pilihan Raya (SPR), serta peranannya untuk menguruskan pendaftaran pemilih, persempadanan dan perjalanan pilihan raya termaktub jelas ...
Yusof, Muhammad Fathi
core