Results 131 to 140 of about 253,751 (300)

Cost Savings in Chronic Pain Patients Initiating Peripheral Nerve Stimulation (PNS) with a 60-Day PNS Treatment

Pain and Therapy
Introduction This study evaluates the financial impact on healthcare payers when chronic pain patients initiate peripheral nerve stimulation (PNS) with a 60-day percutaneous PNS (60-Day PNS) treatment versus a conventional brief PNS trial (PNS-BT) with ...
David M. Dickerson, Hemant Kalia, Kevin E. Vorenkamp, Konstantin V. Slavin, Jonathan M. Hagedorn, Candace Gunnarsson, Eric L. Keuffel, Andrew J. Epstein, Mark Stultz, Nathan D. Crosby   +9 more
doaj   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

SPR 2018 [PDF]

Pediatric Radiology, 2018
openaire   +2 more sources

From Managerial Awareness to Behavior in the Circular Economy: The Role of Personality Traits and Organizational Support

Business Strategy and the Environment, EarlyView.
ABSTRACT As businesses are increasingly integrating circular economy (CE) principles to promote concrete sustainability actions, understanding which managerial aspects may align with this change becomes paramount. Employing a conceptual framework based on Cognitive‐Affective Personality System (CAPS) and Organizational Support theories, this study ...
Fiorenza Meucci, Flavio Spagnuolo, Annamaria Zampella, Marco Maffei   +3 more
wiley   +1 more source

Structure‐Function Tailoring of Plasmonic Nanomaterials for Thin‐Film Photovoltaics

Carbon Energy, EarlyView.
This review discusses the mechanisms and recent advancements of plasmonics in achieving effective light management to enhance the performance of thin‐film solar cells. It highlights applications in high‐performance perovskite solar cells and future‐oriented tandem solar cells.
Sen Jiang, Wenhan Yang, Annan Zhu, Yuexin Lin, Zhaohui Xie, Ran Chen, Wenjing Zhu, Jin Liu, Yingjie Zhu, Wenye Jiang, Zhiyuan Gu, Kaiyang Wang, Shengchun Yang, Nan Zhang, Chao Liang   +14 more
wiley   +1 more source

The One‐Step Synthesis of Biologically Active Isochromans from Lignin‐Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

Chemistry – A European Journal, EarlyView.
A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi, Anastasiia M. Afanasenko, Antonio A. Castillo‐Garcia, Walid A. M. Elgaher, Jörg Haupenthal, Anna K. H. Hirsch, Katalin Barta   +6 more
wiley   +1 more source

The Structure of Regular in Symbolic 2-Plithogenic Rings and the Most Important Properties of Their Elements

Journal of Mathematics
In this paper, we generalize the regularity to a symbolic 2-plithogenic structure. We present the structure and elementary properties of regular symbolic 2-plithogenic rings. We also found that the classical regular ring R is equivalent to the symbolic 2-
Murhaf Riad Alabdullah
doaj   +1 more source

Sunlight‐Driven Green Synthesis of Platinum Nanoparticles From Double‐Vacancy Halide Perovskite Precursors for Methanol Reforming

Chemistry – A European Journal, EarlyView.
ABSTRACT The development of synthetic procedures for preparing metal nanoparticles with controlled size using sunlight opens new avenues toward more sustainable methods with lower energy consumption. Herein, we propose the use of double‐vacancy halide perovskites as precursors for engineering highly crystalline and small platinum nanoparticles (< 3 nm)
Kevin Mego, Saray Chacón‐Ruiz, Pedro Ruiz‐Campos, Herme G. Baldoví, Pedro Atienzar   +4 more
wiley   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

Chemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke, Carmelo Di Primo, Felix Bernhardt, Alea Schröder, Christian Renzl, Günter Mayer   +5 more
wiley   +1 more source