Results 41 to 50 of about 104,735 (306)

A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Novel series of pleuromutilin analogs containing substituted 1,2,3-triazole moieties were designed, synthesised and assessed for their in vitro antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA).
Zhe Zhang   +5 more
doaj   +1 more source

DNA-based biosensor platforms for the detection of TP53 mutation [PDF]

open access: yes, 2012
A DNA-based assay for the detection of one-point mutation in TP53 gene, responsible for lung cancer, was developed using a surface plasmon resonance (SPR) and a quartz crystal microbalance (QCM) biosensor systems.
Altintas, Zeynep   +3 more
core   +1 more source

sj-pdf-1-spr-10.1177_02654075221078295 – Supplemental Material for Inventory of dating stress: Initial psychometric evaluation and construct validity

open access: yes, 2022
Supplemental Material, sj-pdf-1-spr-10.1177_02654075221078295 for Inventory of dating stress: Initial psychometric evaluation and construct validity by Timothy J.
Timothy J. Sullivan (121824)   +1 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

sj-pdf-1-spr-10.1177_02654075211050070 – Supplemental Material for The complicated connection between closeness and the quality of romantic relationships

open access: yes, 2021
Supplemental Material, sj-pdf-1-spr-10.1177_02654075211050070 for The complicated connection between closeness and the quality of romantic relationships by David M. Frost and Allen J.
Allen J. LeBlanc (11598926)   +1 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

sj-pdf-1-spr-10.1177_02654075221080744 – Supplemental Material for Perceived barriers and rewards to sexual consent communication: A qualitative analysis

open access: yes, 2022
Supplemental Material, sj-pdf-1-spr-10.1177_02654075221080744 for Perceived barriers and rewards to sexual consent communication: A qualitative analysis by Jessica Edwards, Uzma S Rehman and E Sandra Byers in Journal of Social and Personal ...
Jessica Edwards (259720)   +2 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Four-Year Follow-Up from a Prospective, Multicenter Study of Percutaneous 60-Day Peripheral Nerve Stimulation for Chronic Low Back Pain

open access: yesPain and Therapy
Introduction Chronic low back pain (LBP) is a leading cause of healthcare expenditure and long-term disability associated with complex treatment challenges and the need for progressively invasive interventions.
Christopher A. Gilmore   +8 more
doaj   +1 more source

sj-pdf-1-spr-10.1177_02654075211042317 – Supplemental Material for Romantic and parental attachment, psychosocial risk, and personal agency in emerging adulthood

open access: yes, 2021
Supplemental Material, sj-pdf-1-spr-10.1177_02654075211042317 for Romantic and parental attachment, psychosocial risk, and personal agency in emerging adulthood by Filipa Nunes, Paula Mena Matos, Tiago Ferreira and Catarina Pinheiro Mota in Journal of ...
Catarina Pinheiro Mota (10389741)   +3 more
core   +1 more source

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