Results 71 to 80 of about 251,829 (282)
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Advanced Science, EarlyView.Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
Learning the LMP-Load Coupling From Data: A Support Vector Machine Based Approach
, 2016 This paper investigates the fundamental coupling between loads and locational marginal prices (LMPs) in security-constrained economic dispatch (SCED).
Geng, Xinbo, Xie, Le
core +1 more source
Advanced Science, EarlyView.Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
THE MYTH OF BIOFUELS IN MEXICO
Tropical and Subtropical Agroecosystems, 2019 Biofuels are one of the strategies proposed for adaptation and mitigation to global warming; Originated by greenhouse gases, considered as the most important anthropogenic disturbance that the man has realized on the natural resources.
Julio Vilaboa-Arroniz +3 more
doaj
Sensitivity Enhancement of a Surface Plasmon Resonance Sensor with Platinum Diselenide
Sensors, 2019 The extraordinary optoelectronic properties of platinum diselenide (PtSe2), whose structure is similar to graphene and phosphorene, has attracted great attention in new rapidly developed two-dimensional (2D) materials beyond the other 2D material family ...
Yue Jia +4 more
doaj +1 more source
Eos, Transactions American Geophysical Union, 1983 The First Occasional Solar Planetary Relationships Award Ceremony was held in conjunction with the annual SPR banquet on December 8, 1982. The following awards were presented:The Golden Palate Award to Bruce T. Tsurutani for his intrepid tasting and superb menu planning;The Traveling Intercontinental Disturbance Award to Murray Dryer and Peggy Shea for
openaire +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
Modelling of self-piercing riveting with ale, cel and sph based on abaqus/explicit [PDF]
, 2017 SPR (Self-piercing riveting) is a cold forming process that is used to fasten together two or more sheets of different materials mechanically with a rivet. Also SPR emulates the results and quality of spot welding without many of the risks, such as toxic
Aihara, Hiroshi, Ishikawa, Satoshi
core
Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition
Advanced Science, EarlyView.Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han +9 more
wiley +1 more source