Results 71 to 80 of about 104,735 (306)

SPR biosensor based on polymer multi-mode optical waveguide and nanoparticle signal enhancement [PDF]

, 2020
We present a surface plasmon resonance (SPR) biosensor that is based on a planar-optical multi-mode (MM) polymer waveguide structure applied for the detection of biomolecules in the lower nano-molar (nM) range. The basic sensor shows a sensitivity of 608.
Alwis, Lourdes, Walter, Johanna-Gabriela, Alina Eilers, Bremer, Kort, Alwis, Lourdes Shanika Malindi, Eilers, Alina, Kort Bremer, Johanna-Gabriela Walter, Lourdes Alwis, Wilhelm Roth, Bernhard, Roth, Bernhard Wilhelm, Gabriela Walter, Johanna, Bernhard Roth   +12 more
core   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Enhanced Photocatalytic Performance of Ag-Modified ZnO for the Degradation of Tartrazine Dye

Bulletin of Chemical Reaction Engineering & Catalysis
In this study, ZnO materials were synthesized using the hydrothermal method, and then modified with Ag using glucose, a biologically derived and environmentally friendly reducing agent, to produce Ag/ZnO materials with varying Ag contents.
Cam Vi Dao Thi, Tuan Anh Nguyen, Quang Minh Pham, Anh-Tuan Vu   +3 more
doaj   +1 more source

Serological methods for detection of the causative agent of tularemia and their evaluation

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. A comparative study of serological methods for the detection of the causative agent of tularemia and their evaluation. Materials and methods. We used experimental diagnostic kits and test systems for the production of serological methods: indirect ...
I. V. Zharnikova, V. I. Efremenko, T. V. Zharnikova, S. A. Kurcheva, S. M. Kalnoy, D. V. Еfremenko, A. A. Isakova, A. V. Indenbom   +7 more
doaj   +1 more source

sj-pdf-1-spr-10.1177_02654075221074392 – Supplemental Material for Perceptions of interest and agency explain disagreements about sexual violations

, 2022
Supplemental Material, sj-pdf-1-spr-10.1177_02654075221074392 for Perceptions of interest and agency explain disagreements about sexual violations by Anjuli Corzine and Audun Dahl in Journal of Social and Personal ...
Audun Dahl (12043512), Anjuli Corzine (12043509)   +1 more
core   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

SPR-based competition assay of recombinant ficolin-3 interaction with O-PS 1200 and IgG.

, 2016
Two-step SPR analysis of the interaction of immobilized recombinant ficolin-3 with 670 μM O-PS 1200 and 6.67 μM human IgG. No regeneration step was included between O-PS and IgG. Sensor chip: CM5. RU, resonance units.
Aleksandra Man-Kupisinska (3166536), Mateusz Michalski (3166539), Anna Maciejewska (3166530), Anna S. Swierzko (3166533), Jolanta Lukasiewicz (683551), Maciej Cedzynski (3166527), Czeslaw Lugowski (2529148)   +6 more
core   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

sj-pdf-1-spr-10.1177_02654075211055759 – Supplemental Material for Reciprocal self-disclosure and rejection strategies on Bumble

, 2021
Supplemental Material, sj-pdf-1-spr-10.1177_02654075211055759 for Reciprocal self-disclosure and rejection strategies on Bumble by Audrey Halversen, Jesse King and Lauren Silva in Journal of Social and Personal ...
Lauren Silva (11783010), Jesse King (11783007), Audrey Halversen (11783004)   +2 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source