Results 111 to 120 of about 317,880 (361)

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis   +6 more
wiley   +1 more source

Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats

open access: yesToxicology Reports, 2020
Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan   +9 more
doaj  

The effect of developmental vitamin D deficiency in male and female Sprague-Dawley rats on decision-making using a rodent gambling task [PDF]

open access: yes, 2015
Developmental vitamin D (DVD) deficiency is a plausible risk factor for schizophrenia that has been associated with behavioural alterations including disruptions in latent inhibition and response inhibition.
Burne, T. H. J.   +2 more
core   +1 more source

Mesoporous Fe3O4 Nanoparticles Loaded with IR‐820 for Antibacterial Activity via Magnetic Hyperthermia Combined with Photodynamic Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study addresses bacterial biofilm resistance by developing mesoporous Fe3O4 nanoparticles loaded with photosensitizer IR‐820, enabling combined antimicrobial photodynamic therapyand magnetic hyperthermia therapy. The system achieves magnetic targeting, heat‐triggered drug release under alternating magnetic fields, and near‐infrared‐induced ROS ...
Yuange Li   +8 more
wiley   +1 more source

Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light

open access: yesInternational Journal of Zoology, 2010
Light intensity and wavelength strongly influence mood and cognition in humans and rodent animal models. The aim of the present study was to explore if dim white (7.6–17.7 lux) , blue (1.3–2.3 lux), and red light (0.8–1.4 lux) affect spatial memory of ...
Michael Pirchl   +2 more
doaj   +1 more source

Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]

open access: yes, 2016
Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core   +1 more source

Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]

open access: yes, 2018
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

open access: yesAdvanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll   +16 more
wiley   +1 more source

Chordoma in a Sprague-Dawley Rat [PDF]

open access: yesToxicologic Pathology, 1991
Randy C. Eyster, Gary M. Zwicker
openaire   +3 more sources

A Highly Adaptable Hydrogen Bond Re‐Orientation (HyBRO) Strategy for Multiscale Vasculature Fabrication

open access: yesAdvanced Materials, EarlyView.
A novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Zhencheng Liao   +5 more
wiley   +1 more source

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