Results 111 to 120 of about 317,880 (361)
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis+6 more
wiley +1 more source
Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats
Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan+9 more
doaj
The effect of developmental vitamin D deficiency in male and female Sprague-Dawley rats on decision-making using a rodent gambling task [PDF]
Developmental vitamin D (DVD) deficiency is a plausible risk factor for schizophrenia that has been associated with behavioural alterations including disruptions in latent inhibition and response inhibition.
Burne, T. H. J.+2 more
core +1 more source
This study addresses bacterial biofilm resistance by developing mesoporous Fe3O4 nanoparticles loaded with photosensitizer IR‐820, enabling combined antimicrobial photodynamic therapyand magnetic hyperthermia therapy. The system achieves magnetic targeting, heat‐triggered drug release under alternating magnetic fields, and near‐infrared‐induced ROS ...
Yuange Li+8 more
wiley +1 more source
Light intensity and wavelength strongly influence mood and cognition in humans and rodent animal models. The aim of the present study was to explore if dim white (7.6–17.7 lux) , blue (1.3–2.3 lux), and red light (0.8–1.4 lux) affect spatial memory of ...
Michael Pirchl+2 more
doaj +1 more source
Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]
Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core +1 more source
Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core +1 more source
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll+16 more
wiley +1 more source
Chordoma in a Sprague-Dawley Rat [PDF]
Randy C. Eyster, Gary M. Zwicker
openaire +3 more sources
A novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Zhencheng Liao+5 more
wiley +1 more source